- P-ISSN 1225-0163
- E-ISSN 2288-8985
Cyanobacterial toxins, microcystins which exist in Korean lakes show strong toxicity to fish, cattles and human. In this study, we tried to analyze cyanobacterial toxin, microcystin in the Microcystis cultivation solution using test strip, although the most common analytical methods for the detection of microcystin are HPLC and ELISA. This new anlytical method used the advantages of high specifisity and rapidness of test strip, high sensitivity of fluorescence reader. Therefore, we could analyze the trace amount of microcystin existed in various water samples without using the microcystin standards.
1. G. Francis, Nature(London), 18, 11 (1878).
2. M. Schwimmer and D. Schwimmer, In ‘Medical Aspects of Phycology’, p279, 358, D. F. Jackson, Ed., Syracuse Univ, 1968.
3. W. W. Chrmichael and R. S. Saffermann, A Status Report on Planktonic Cyanobacteria (Blue-Green Algae) and Their Toxins, EPA/600/R 92/079 (1992).
4. F. D. Galey, V. R. Beasley, W. W. Carmichael, G. Kleppe, S. B. Hooser and W. M. Haschek, Am. J. Vet. Res., 48, 1415 (1987).
5. D. P. Botes, C. C. Viljoen, M. Kruger, P. L. Wessels and D. H. Williams, Toxicon., 20, 1037 (1982).
6. D. P. Botes, A. A. Tainman, P. L. Wessels, C. C. Viljoen, M. Kruger, D. H. Williams, S. Santikarn, R. J. Smith and S. J. Hammond, J. Chem. Soc., Perkin Trans., 1, 2311 (1984).
7. T. Kusumi, T. Ooi, M. M. Watanabe, H. Takahashi and H. Kakisawa, Tetrahedron Lett., 26, 4695 (1987).
8. T. Krishnamurthy, W. W. Carmichael and E. W. sarver, Toxicon, 24, 865 (1986).
9. J. A. O. Meriluoto, A. Sandstrm, J. E. Eriksson, G. Remand, A. Grey Craog and J. Chattopadhyaya, Toxicon, 27, 1021 (1989).
10. K. Sivonen, W. W. Carmichael, M. Namikoshi, M. L. Rinehart, A. M. Dahlem and S. I. Niemela, Appl. Environ. Microbiol., 56, 2650 (1990).
11. J. J. Jr. Sansner, M. Ikawa and T. L. Foxall, In ‘Studies on Aphanizomenon and Microcystic Toxins, Seafood Toxins’, pp. 391-406, E. P. Ragelis, Ed., American Chemical Society Symposium Series 262, Washington, DC., 1984.
12. J. P. Devlin, O. E. Edwards, P. R. Gorham, N. R. Hunter, P. K. Pike and B. Stavric, Can. J. Chem., 55, 1367 (1977).
13. S. Matsunaga, R. E. Moore, W. P. Niemozura and W. W. Carmichael, J. Am. Soc., 111, 8021 (1989).
14. N. A. Mahmood and W. W. Carmichael, Toxicon, 25, 1221 (1986).
15. K. S. Cho, B. C. Kim, W. M. Heo and S. J. Cho, Korean J. Limnology, 22(3), 179 (1989).
16. R. Ruangyuttikarn, M. Ivan, P. Jeeraporn, P. Yuwadee and D. Zdenek, J. Chromatogr. B, 800, 315-319 (2004).
17. L. Spoof, P. Vesterkvist, T. Lindholm and J. Meriluoto, J. Chromatogr. A, 1020(1), 101-115 (2003).
18. K. I. Harada, N. Tomoyo, F. Kiyonaga and S. Makoto, J. Chromatogr., 1033, 107-113 (2004).
19. H. Mhadhbi, S. Ben-Rejeb, C. Cléroux, A. Martel and P. Delahaut, Talanta, 70, 225-235 (2006).
20. J. W. Shenga, M. He and H. C. Shia, Analytica Chimica Acta, 603(1), 111-118 (2007).
21. L. A. Lawton, Toxicol. Appl. Pharmacol., 203(3), 219-230 (2005).
22. R. Y. Stainier, R. Kunisawa, M. Mandel and G Cohen-Bazire Bacteriol. Rev., 35, 171-205 (1971).
23. M. Shirai, K. Matumaru, A. Ohotake, Y. Takamura, T. Aida and M. Nakano, APP. Environmental Microbiology, 55, 2569-2571 (1989).
24. M. F. Watnabe and S. Oishi, APP. Enviyon. Microbiol, 49, 1342-1344 (1985).