- P-ISSN 1225-0163
- E-ISSN 2288-8985
- 권한신청
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
논문 상세
Home > 논문 상세
Separation and recovery of semi-volatile substances of Cnidii Rhizoma, Aucklandiae Radix and Amomum Fructus by reduced pressure collections and GC-MS
분석과학 / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2020, v.33 no.1, pp.11-22
https://doi.org/10.5806/AST.2020.33.1.11
(대전대학교)
(대전대학교)
(Korea Institute of Geoscience and Mineral Resources)
(Department of Civil, Safety and Environmental Engineering, Hankyong National University)
(Department of Applied Chemistry, Daejeon University)
(대전대학교)
(Korea Institute of Geoscience and Mineral Resources)
(Department of Civil, Safety and Environmental Engineering, Hankyong National University)
(Department of Applied Chemistry, Daejeon University)
이인호,
변창규,
Chul,
H.
E.
,
Taewook,
K.
,
&
Sam,
K.
L.
(2020). . 분석과학, 33(1), 11-22, https://doi.org/10.5806/AST.2020.33.1.11
- 다운로드 수
- 조회수
Abstract
When extracting semi-volatile components of herbal medicines using hot water vapor, some substances may react with water vapor or oxygen, and some volatile substances may be lost, when using an organic solvent extraction method has the disadvantage that it may contain a non-volatile material and residual organic solvent. In addition, it is inefficient to separate semi-volatile substances from herbal medicines into each single component and conduct biological activity research for each component to determine the effective ingredient, and some components may be lost in the separation process. In this study, semi-volatile substances evaporated under two pressure-reduced conditions in Chinese herbal medicines such as Cnidii Rhizoma, Aucklandiae Radix and Amomum Fructus were separated by cooling with liquid nitrogen. Those were analyzed by gas chromatographymass spectrometry (GC-MS) to identify the components, and this method may be used to study biological activities at the cellular level. The substances separated under reduced pressure, essential oil obtained by simultaneous distillation extraction (SDE) method and substances by using solid phase micro-extraction (SPME) from Cnidii Rhizoma, Aucklandiae Radix and Amomum Fructus were analyzed by GC-MS. In the case of Cnidii Rhizoma and Aucklandiae Radix, there were some differences among the essential oil components obtained by SDE and those identified by low temperature capture (CT) and SPME method, these were believed to be produced by some volatiles reacting with water or oxygen at the boiling point temperature of water.
- keywords
- Cnidii Rhizoma, Aucklandiae Radix, Amomum Fructus, cold trap, GC-MS
참고문헌
1
1. M. Takahashi, A. Yamanaka, C. Asanuma, H. Asano, T. Satou and K. Kokike, Nat. Prod. Commun., 9(7), 1023-1026 (2014).
2
2. T. Satou, S. Murakami, M. Matsuura, S. Hayashi and K. Koike, Nat. Prod. Commun., 5(1), 143-146 (2010).
3
3. L. Lucian, O. Cioanca and M. Hancianu, Phytomedicine, 19(6), 529-534 (2012).
4
4. L. R. Chioca, V. D. C. Antunes, M. M. Ferro, E. M. Losso and R. Andreatini, Life Sci., 92(20-21), 971-975 (2013).
5
5. B. S. Koo, S. I. Lee, J. H. Ha and D. U. Lee, Bio. Pharm. Bull., 27(4) 515-519 (2004).
6
6. K. Schnaubelt, Int. J. Aromather., 15(2), 98-105 (2005).
7
7. S. M. Choi, S. Y. Kim, N. R. Park, J. M. Kim, D. H. Yang, C. H. Woo, M. R. Kim and H. D. An, J. Korean Med. Rehabil., 28(3) 13-25 (2018).
8
8. Y. Sim and S. Shin, Yakhak Hoeji, 55(5), 398-403 (2011).
9
9. J. Liu, D. Huang, D. Hao and Q. Hu, Adv. Biosci. Biotechnol., 5, 1043-1047 (2014).
10
10. S. Lu, T. Zang, W. Gu, X. Yang, J. Lu, R. Zhao and J. Yu, BioMed. Res. Int., 2018, 1-16 (2018).
11
11. T. Zhang, S. H. Lu, Q. Bi, L. Liang, Y. F. Wang, X. X. Yang, W. Gu and J. Yu, Front. Pharmacol., 8, 1-13 (2017).
12
12. M. Benzo, G. Gilardoni, C. Gandini, G, Caccialanza, P. V. Finzi, G. Vidari, S. Abdo and P. Layedra, J. Chromatogr. A, 1150(1-2), 131-135 (2007).
13
13. Z. O. Mustafa and H. Hilal, Anal. Bioanal. Chem., 379(7-8), 1127-1133 (2004).
14
14. P. Tatke and Y. Jaiswal, Res. J. Med. Plants, 5(1), 21-31(2011).
15
15. A. Chaintreau, Flavour Fragnance J., 16(2), 136-148(2001).
16
16. C. Gherman, M. Culea and O. Cozar, Talanta, 53(1), 253-262 (2000).
17
17. J. L. Hendrick, J. M. Leah and L. T. Taylor, Microchim. Acta., 108(3-6), 115-132 (1992).
18
18. J. B. Jeong, S. Y. Ju, J. H. Park, J. R. Lee, K. W. Yun, S. T. Kwon, J. H. Lim, G. Y. Chung and H. J. Jeong, Cancer Epidemiol., 33, 41-46 (2009).
19
19. H. S. Choi, M. S, Lee Kim and M. Sawamura, Flavour Frager. J., 17, 49-53 (2002).
20
20. 20. B. R. Yeon, K. Sowndhararajan, J. W. Jung, J. W. Jhoo and S. Kim, Int. J. Pharm. Pharm. Sci., 6(9), 355-358 (2014).
21
21. B. R. Yeon ‘Effect of Volatile Organic Chemicals in the Essential Oil of Cnidium officinale Makino on Electroencephalogram’ Master Dissertation, Kangwon National University, Korea, 2013.
22
22. H. K. Jung ‘Isolation and Characterization of Fragrant Constituents and Volatile Organic Compounds from Cnidii Rhizoma’ Master Dissertation, Ulsan University, Korea, 2008.
23
23. J. H. Lee, H. S. Choi, M. S. Chung and M. S. Lee, Korean J. Food Sci. Technol., 34(2), 330-338 (2002).
24
24. H. H. Leem, E. O. Kim, M. J. Seo and S. W. Choi, J. Soc. Cosmet. Scientists Korea, 37(3), 199-210 (2011).
25
25. X. R. Li, Y. Z. Liang and F. Q. Guo, Acta Pharmacol. Sin., 27(4), 491-498 (2006).
26
26. N. K. Dubey, R. Kumar and P. Tripathi, Curr. Sci., 86(1), 37-41 (2004).
27
27. M. M. W. B. Hendriks, L. C. Juarez, D. D. Bont and R. D. Hall, Anal. Chim. Acta., 545(1), 53-64 (2005).
28
28. C. Deng, N. Yao, A. Wang and X. Zhang, Anal. Chim. Acta., 536(1-2), 237-244 (2005).
29
29. C. Deng, A. Wang, A. Shen, D. Fu, J. Chen and X. Chang, J. Pharm. Biomed. Anal., 38(2), 326-331 (2005).
30
30. X. H. Lin, Y. B. Wu, S. Lin, J. W. Zeng, P. Y. Zeng and J. Z. Wu, Molecules, 15, 241-250 (2010).
31
31. X. F. Liu, H. H. Chen, J. K. Li, R. Zhang, T. C. Turlings and L. Chen, Pest Manag. Sci., 72, 1959-1964 (2016).
32
32. M. Khan, Orient. J. Chem., 31(1), 541-545 (2015).
33
33. S. Wu., T. Xu. And C. C. Akoh, J. Food Drug Anal., 22, 310-317 (2014).
34
34. P. R. Venskutonis, Food. Chem., 59(2), 219-227 (1997).
35
35. Y. Z. Liang and K. Chan, J. Chromatogr. B, 812, 53-70(2004).
36
36. W. Y. Kim, J. M. Kim, S. B. Han, S. K. Lee, N. D. Kim, M. K. Park, C. K. Kim and J. H. Park, Natural Products, 63(12), 1702-1704 (2000).
37
37. K. M. Chang and G. H. Kim, J. Food. Sci. Nutr., 13, 128-133 (2008).
38
38. J. Liu, D. Huang, D. Hao and Q. Hu, Adv. Biosci. Biotechnol., 5, 1042-1047 (2014). 39
39
39. J. H. Yoon, H. Y. Park, T. J. Kim, S. H. Lee, J. H. Kim, G. S. Lee, H. J. Kim and Y. S. Ju, J. Korean Med., 35(4), 83-97 (2014).
40
40. S. K. Chiu ‘Authentication of Traditional Chinese Medicines Radix Aconiti and Radix Aucklandiae by DNA and Chemical Technologies’ Master Dissertation, The Chinese University of Hong Kong, Hong Kong, 2006.
41
41. Y. J. Chung, K. S. Lee, S. H. Han, D. I. Kang and M. H. Lee, J. Conserv. Sci., 10(1), 21-30 (2001).
42
42. S. W. Choi, E. O. Kim, H. H. Leem and J. K. Kim, J. Korean Soc. Food Sci. Nutr., 41(8), 1057-1065 (2012).
43
43. K. C. Shum, F. Chen, S. L. Li, J. Wang, P. H. Paul and P. C. Shaw, J. Sep. Sci., 30(18) 3233-3239 (2007).
44
44. G. Kumar, B. Chauhan and M. Ali, Am. J. PharmTech Res., 2(4), 626-632 (2012).
45
45. B. Sabulal, M. Dan, N. S. Pradeffp, R. K. Valsamma and V. George, Acta Pharm., 56, 473-480 (2006).
46
46. V. George, J. Mathew, B. Sabulal, M. Dan and S. Shilburaj, Fitoterapia, 77, 392-394 (2006).
47
47. J. Mathew, S. Shilburaj and V. George, Fitoterapia, 74, 476-478 (2003).
48
48. C. Deng, N. Yao, A. Wang and X. Zhang, Anal. Chim. Acta, 536, 237-244 (2005).
49
49. C. Deng, A. Wang, S. Shen, D. Fu, J. Chen and X. Zhang, J. Pharm. Biomed. Anal., 38, 326-331 (2005).
50
50. S. K. Lee, C. H. Eum and C. G. Son, Anal. Sci. Technol., 28(6), 436-445 (2015).
권호 내 다른 논문
- Enantiomeric purity test of R-(+)-alpha lipoic acid by HPLC using immobilized amylose-based chiral stationary phase
- Separation and recovery of semi-volatile substances of Cnidii Rhizoma, Aucklandiae Radix and Amomum Fructus by reduced pressure collections and GC-MS
- Development and validation of a qualitative GC-MS method for methamphetamine and amphetamine in human urine using aqueous-phase ethyl chloroformate derivatization
- Chemical characteristics of wet precipitation in urban and mountainous sites of Jeju Island
- Determination of trace bromate in various water samples by direct-injection ion chromatography and UV/Visible detection using post-column reaction with triiodide
- The effect of ventilation on reducing the concentration of hazardous substances in the indoor air of a Korean living environment
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.