ISSN : 3022-6805
Cognitive Improvement Effect of Resplex Alpha A in the Scopolamine-induced Mouse Model
셀메드 / CELLMED, (P)3022-6805; (E)3022-6791
2023, v.13 no.14, pp.1-1
https://doi.org/10.5667/CellMed.2023.014
장봉근
(JBK-LAB, Inc.)
권영선 (JBK-LAB, Inc.)
박선영 (JBK-LAB, Inc.)
이건우 (JBK-LAB, Inc.)
강혜연 (JBK-LAB, Inc.)
김점용 (JBK-LAB, Inc.)
권영선 (JBK-LAB, Inc.)
박선영 (JBK-LAB, Inc.)
이건우 (JBK-LAB, Inc.)
강혜연 (JBK-LAB, Inc.)
김점용 (JBK-LAB, Inc.)
장봉근,
권영선,
박선영,
이건우,
강혜연,
&
김점용.
(2023). . 셀메드, 13(14), 1-1, https://doi.org/10.5667/CellMed.2023.014
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Abstract
Administration of Scopolamine can be considered a psychopharmacological model of Alzheimer's disease (AD). We made an animal model of Alzheimer's disease (AD) by administering Scopolamine to Blab/c mice. In this study, we investigated the effects of Resplex Alpha on memory impairment and cognitive function in mice in a mouse animal model of Scopolamine-induced memory impairment. Through Y-mazed and passive avoidance behavioral assays, we observed that Resplex Alpha recovered Scopolamine-induced short-term memory and cognitive functions. The results of our study imply that Resplex Alpha may be beneficial in the prevention of Alzheimer's disease (AD).
- keywords
- Resveratrol-alginate nano-complex (RANCP), Ginkgo biloba extract (EGb231), Cognitive function, Memory dysfunction, Alzheimer’s disease (AD), dementia
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