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- P-ISSN3022-6805
- E-ISSN3022-6791
- KCI
ISSN : 3022-6805
A comparison study of the effects of loratadine-pharmacopuncture and loratadine-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice
Hyun-Min Kim (Kyung Hee University)
Min-Jung Lee (Kyung Hee University)
Min-Gi Cho (Kyung Hee University)
Deok Kang (Kyung Hee University)
Yu-Kyung Kim (Kyung Hee University)
et al. (Kyung Hee University)
Phil-Dong Moon (Kyung Hee University)
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Abstract
Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between loratadine-pharmacopuncture (LP) and loratadine-oral administration (LO), the effect of loratadine was investigated in murine models. Anti-anaphylactic effects of loratadine treatments were investigated in compound 48/80-induced systemic anaphylactic reaction and passive cutaneous anaphylaxis (PCA). LP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction and PCA. The effect between LP and LO were on a similar level. These results indicate that LP can be used as an alternative method for LO in case of emergency.
- keywords
- loratadine-pharmacopuncture, systemic anaphylactic reaction, passive cutaneous anaphylaxis
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