The regulatory effect of AST cream on atopic dermatitis-like skin disease.

In this study, we investigated an inhibitory effect of AST cream on atopic dermatitis (AD) using a 2,4-dinitrochlorobenzene-induced AD murine model. Topical treatment with AST cream ameliorated the severity of AD-like lesional skin through decreases in infiltration of inflammatory cells and time of scratching behaviors. Also, AST cream reduced histamine and IgE levels in serum. The protein levels of IL-4 and IL-6 in AD-like lesional skin were suppressed by AST cream. These findings suggest that AST cream would be an alternative therapeutic agent for AD-like skin diseases.

keywords: AST cream, histamine, IgE, atopic dermatitis

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Article Contents

Vol.9 No.3

The regulatory effect of AST cream on atopic dermatitis-like skin disease.

Abstract

Reference

CELLMED