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  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
 

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가상환경을 이용한 일화기억 인출에서 조현병 환청군과 비환청군의 신경 진동의 차이

Differences in Oscillatory Correlates of Episodic Retrieval in a Virtual Navigation Task between Schizophrenia with and without Hallucinations

한국심리학회지: 인지 및 생물 / The Korean Journal of Cognitive and Biological Psychology, (P)1226-9654; (E)2733-466X
2015, v.27 no.1, pp.1-21
https://doi.org/10.22172/cogbio.2015.27.1.001
정지운 (고려대학교)
이승환 (인제대학교 의과대학 정신과)
김지영 (고려대학교 심리학과)
한현정 (고려대학교 심리학과)
김현택 (고려대학교)
  • 다운로드 수
  • 조회수

Abstract

Neural correlates of episodic memory deficits may be different in schizophrenia patients with hallucinations (SH) and patients without hallucinations (SnH). However, little is known about how specific neural correlates involved in episodic retrieval may differ between SH and SnH. We aimed to determine whether neural oscillations in SH during episodic retrieval are different from those in SnH and normal controls (NC) after navigating rooms in a virtual environment (VE). The VE was used to enhance patient motivation in episodic memory test by engaging higher cognitive involvement. Subjects experienced a navigation session and a retrieval session. Electroencephalogram (EEG) was recorded during the retrieval session, and time-frequency analyses were examined (7 NC, 7 SnH, and 7 SH). Consistent with previous reports, the results revealed that theta power was correlated with successful episodic retrieval, suggesting that the reductions of theta power may contribute to episodic memory deficits in SH and SnH. Notably, the theta power differences between the old and new conditions was positively correlated with episodic retrieval performances across SH, SnH, and NC. Other oscillatory activities (i.e., alpha and beta) may also contribute to episodic retrieval with a diversity of functional relevance across groups. Overall results showed deficits in episodic retrieval, corresponding oscillations in EEG frequency bands. The neural oscillations across different frequencies and their relationship to cognitive processes, including inhibition and attention in episodic memory, are also discussed.

keywords
Episodic memory, Schizophrenia, Hallucination, EEG, Time-frequency analysis, Virtual environment, 일화기억, 조현병, 환각, 뇌파, 시간-주파수 분석, 가상환경

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