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다발성 골전이를 동반한 진행된 원발성 반지세포 폐암종(Primary Signet Ring Cell Carcinoma of Lung) 1예

A Case of Primary Signet Ring Cell Carcinoma of Lung with Multiple Bone Metastasis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2004, v.57 no.6, pp.594-598
신도현 (아주대학교)
김형일 (아주대학교)
박주헌 (아주대학교)
신승수 (아주대학교)
오윤정 (이화여자대학교)
박광주 (아주대학교)
황성철 (아주대학교)
박래웅 (아주대학교)
심철 (아주대학교)
임선교 (아주대학교)
이승원 (아주대학교)
정연무 (아주대학교)
최영인 (아주대학교)
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초록

원발성 반지세포 폐암종은 점액을 분비하는 독특한 선암의 일종으로 매우 드물게 발생한다. 예후가 불량하므로 타 원발성 및 전이성 폐암종과 감별이 필요하고 임상적인 검사로 원발병소를 찾기가 어려울 경우 조직면역학적 방법이 감별에 도움이 된다. 본 저자들은 다발전 골전이를 동반한 진행된 원발성 반지세포 폐암종의 증례를 문헌고찰과 함께 보고하는 바이다.

keywords
Signet ring cell carcinoma, Lung cancer.다발성 골전이를 동반한 진행된 원발성 반지세포 폐암종(Primary Signet Ring Cell Carcinoma of Lung) 1예아주대학교 의과대학 호흡기내과학교실, 1병리학교실신도현, 김형일, 임선교, 이승원, 정연무, 최영인, 신승수, 박주헌, 오윤정, 박광주, 황성철, 박래웅1, 심 철1A Case of Primary Signet Ring Cell Carcin

Abstract

Signet ring cell carcinoma of lung is an unique variant of mucin producing adenocarcinoma which is characterized by abundant intracellular mucin accumulation. Only a few cases of primary signet ring cell carcinoma of lung have been reported in the world wide literature. And we have, recently experienced one case of primary signet ring cell carcinoma of lung. A 55 years old man was evaluated for paralysis of lower extremities and was found to have lung cancer in the left upper and lower lobe with pleural, multiple spinal, bone and liver metastases. Signet ring tumor cells were revealed by cytologic examination of pleural fluids. And there were no evidence of signet ring cell carcinoma of other organs. Primary signet ring cell carcinoma of lung seems to have an aggressive behavior and therapeutic modalities could be different from those for signet ring cell carcinomas from other organs. Therefore it is important to separate primary signet ring cell adenocarcinoma of lung from metastatic tumors. (Tuberc Respir Dis 2004; 57:594-598)

keywords
Signet ring cell carcinoma, Lung cancer.다발성 골전이를 동반한 진행된 원발성 반지세포 폐암종(Primary Signet Ring Cell Carcinoma of Lung) 1예아주대학교 의과대학 호흡기내과학교실, 1병리학교실신도현, 김형일, 임선교, 이승원, 정연무, 최영인, 신승수, 박주헌, 오윤정, 박광주, 황성철, 박래웅1, 심 철1A Case of Primary Signet Ring Cell Carcin

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Tuberculosis & Respiratory Diseases