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A Case of Diffuse Infiltrative Lymphocytosis Syndrome Associated with Human Immunodeficiency Virus Infection

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2006, v.61 no.3, pp.289-293










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Abstract

Diffuse infiltrative lymphocytosis syndrome is an autoimmune syndrome that is characterized by the oligoclonal expansion of CD8+ T-lymphocytes in response to human immunodeficiency virus (HIV) antigens. The clinical manifestations include bilateral enlargement of the parotid glands, lymphocytic interstitial pneumonitis, lymphocytic hepatitis, neurological involvement and systemic lymphadenopathies. In addition to a positive HIV test, the diagnostic histopathological findings are CD8+ T-lymphocytic infiltrations in the lymphnodes, liver, lung, muscle and the salivary or lacrimal glands without granulomatous or neoplastic involvement. We report a case of pulmonary involvement of diffuse infiltrative lymphocytosis syndrome that was associated with a human immunodeficiency virus infection. (Tuberc Respir Dis 2006; 61: 289-293)

keywords
Diffuse infiltrative lymphocytosis syndrome, HIV, CD8+., Diffuse infiltrative lymphocytosis syndrome, HIV, CD8+.

Reference

1.

(1996) The primary response to HIV infection is characterized by an expasion of activated CD8+ CD28-cells,

2.

(1992) Viral phenotype and immune response in primary human immunodeficiency virus type 1(HIV-1)infection,

3.

(1996) Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1,

4.

A diffuse infiltrative lymphocytosis syndrome in human immunodeficiency virus a host immune response associated with HLA-DR5,

5.

(1996) The diffuse infiltrative lymphocytosis syndrome:clinical and immunogenetic features in 35 patients,

6.

(1997) Peripheral neuropathy in human immunodeficiency virus-infected patients with the diffuse infiltrative lymphocytosis syndrome,

7.

(1985) Lymphoid interstitial pneumonitis in acquired immunodeficiency syndrome-related complex,

8.

(1998) Prevalence of Sjogren's-like syndrome in a cohort of HIV-1 positive patients:descriptive pathology and immunopathology,

9.

(1998) Prevalence of the diffuse infiltrative lymphocytosis syndrome among human immunodeficiency virus type-1 positive outpatients,

10.

(1992) Diffuse infiltrative lymphocytosis syndrome:a disorder occurring in human immunodeficiency virus-1 infection that may present as a sicca syndrome,

11.

(1983) Immunohistologic analysis of lymphoid infiltrates in primary Sjogren's syndrome using monoclonal antibodies,

12.

(1983) HLA-DR5 alloantigens in different subsets of patients with Sjogren's syndrome and in family members,

13.

(1980) Sjogren's syndrome(sicca syndrome)current issues,

14.

(2005) Upper respiratory tract involvement in the course of diffuse infiltrative lymphocytosis syndrome in HIV-1 infected patients:report of 2 cases,

Tuberculosis & Respiratory Diseases