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심인성 폐부종과 폐포성 출혈을 보인 갈색세포종 1예

A Case of Pheochromocytoma Accompanied with Alveolar Hemorrhage and Cardiogenic Pulmonary Edema

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.64 no.3, pp.219-223
정종필 (광주기독병원)
김유일 (전남대학교)
임성철 (전남대학교)
김영철 (한중대학교)
반희정 (전남의대)
김수옥 (미래로21병원)
손준광 (서남의대)
주진영 (전남의대)
권용수 (전남대학교)
오인재 (전남의대)
김규식 (전남대학교)
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초록

저자들은 대량 객혈로 내원한 환자에서 폐 출혈과 함께 반복적인 심인성 폐부종, 카테콜라민 유도성 심부전이 합병된 드문 형태의 갈색세포종을 경험하여 이러한 임상 증상시 폐나 심장 질환 외에 갈색세포종에 대한 고려가 필요할 것으로 생각되어 문헌고찰과 함께 보고하는 바이다.

keywords
Pheochromocytoma, Alveolar hemorrhage, Cardiogenic pulmonary edema

Abstract

Pheochromocytoma is derived from the chromaffin tissue. The typical finding of pheochromocytoma is paroxysmal hypertension accompanied with various signs and symptoms that are due to the excess of catecholamines or other bioactive substances. Yet the diagnosis is sometimes difficult to make because its clinical presentation is quite variable. Especially, hemoptysis is a very rare symptom, so the diagnosis is often missed or delayed. Without making the correct diagnosis and then subsequently administering treatment, the condition may be fatal. We herein report on a 68 year-old woman who was admitted because of abdominal pain and hemoptysis. The initial radiologic findings suggested pulmonary edema with alveolar hemorrhage. The urine catecholamine levels were elevated and she developed catecholamine-induced cardiomyopathy. We performed bronchial arterial embolization and we administered alpha blocker medication for controlling the hemoptysis and hypertension. After the temporary symptomatic improvement, her clinical course was aggravated by pneumonia and pulmonary edema. In spite of performing definitive surgery for pheochromocytoma, she died of postoperative hemodynamic instability.

keywords
Pheochromocytoma, Alveolar hemorrhage, Cardiogenic pulmonary edema

참고문헌

1.

1. Kizer JR, Koniaris LS, Edelman JD, St John Sutton MG.Pheochrocytoma crisis, cardiomyopathy, and hemodynamic collapse. Chest 2000;118:1221-3.

2.

2. Wu GY, Doshi AA, Haas GJ. Pheochromocytoma induced cardiogenic shock with rapid recovery of ventricular function. Eur J Heart Fail 2007;9:212-4.

3.

3. Frymoyer PA, Anderson GH Jr, Blair DC. Hemoptysis as a presenting symptom of pheochromocytoma. J Clin Hypertens 1986;2:65-7.

4.

4. Jung YS, Kim JG, Song SK, Kwon SK, Choi YS, Jang TW, et al. A case of pheochromocytoma accompanied with hemoptysis. Kosin Med J 2000;15:103-7.

5.

5. Iino S, Nagashima N, Akiba H, Ban Ymiyamoto M.Hemoptysis and palpitation (with hypertension):pheochromocytoma. Nippon Rinsho 1975;Spec No:918-9, 1394-5.

6.

6. Joshi R, Manni A. Pheochromocytoma manifested as noncardiogenic pulmonary edema. South Med J 1993;86:826-8.

7.

7. Takeshita T, Shima H, Oishi S, Machida N, Uchiyama K.Noncardiogenic pulmonary edema as the first manifestation of pheochromocytoma. Radiat Med 2005;23:133-8.

8.

8. Gatzoulis KA, Tolis G, Theopistou A, Gialafos JH,Toutouzas PK. Cardiomyopathy due to a pheochromocytoma.A reversible entity. Acta Cardiol 1998;53:227-9.

9.

9. Minno AM, Bennett WA, Kvale WF. Pheochromocytoma:a study of 15 cases diagnosed at autopsy. N Engl J Med 1954:251:959-65.

10.

10. de Graeff, Muller H, Moolenaar AJ. Pheochromocytoma:a report of seven cases. Acta Med Scand 1959:164:419-30.

11.

11. Kimura Y, Ozawa H, Igarashi M, Iwamoto T, Nishiya K, Urano T, et al. A pheochromocytoma causing limited coagulopathy with hemoptysis. Tokai J Exp Clin Med 2005;30:35-9.

Tuberculosis & Respiratory Diseases