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Tuberculosis & Respiratory Diseases

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Vol.66 No.3
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특발성 세기관지중심성 간질성 폐렴 1예

A Case of Idiopathic Bronchiolocentric Interstitial Pneumonia

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2009, v.66 no.3, pp.230-235
강지영 (가톨릭대학교)
정정임 (가톨릭대학교)
이교영 (가톨릭대학교)
김태정 (가톨릭대학교)
이정우 (가톨릭대학교)
이욱현 (가톨릭대학교)
정의성 (가톨릭의대)
윤형규 (가톨릭대학교)
송정섭 (가톨릭대학교)
강지영, 정정임, 이교영, 김태정, 이정우, 이욱현, 정의성, 윤형규, & 송정섭. (2009). 특발성 세기관지중심성 간질성 폐렴 1예. Tuberculosis & Respiratory Diseases, 66(3), 230-235.
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Abstract

Idiopathic bronchiolocentric interstitial pneumonia is one of idiopathic interstitial pneumonia, which has a relatively aggressive course and poor prognosis. It is characterized by diffuse centrilobular nodules radiologically with mainly bronchiolocentric inflammation and fibrosis associated with patchy alveolitis lacking interstitial granuloma histologically. This disorder is a recently classified disease category, and to our knowledge, there is no case report in Korea. We present a case of idiopathic bronchiolocentric interstitial pneumonia. A 62-year-old man presented with exertional dyspnea with a 1 month duration. The radiological findings showed extensive centrilobular lesions at both lungs. The surgical lung biopsy specimen demonstrated a centrilobular inflammatory process with small airway fibrosis and inflammation partially radiating into the interstitium. Therefore, the patient was diagnosed with idiopathic bronchiolocentric interstitial pneumonia. He was treated with immunosuppressants including steroids and azathioprine. However, his symptoms did not improve and he expired 7 months later due to an acute exacerbation of the interstitial pneumonia and probable infectious pneumonia.

keywords
Bronchiolitis, Interstitial pneumonia, Interstitial lung disease

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