- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Apply for Authority
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Bacterial Reverse Mutation Test of CP pharmacopunture
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2020, v.41 no.3, pp.55-65
&
(2020). Bacterial Reverse Mutation Test of CP pharmacopunture. Journal of Korean Medicine, 41(3), 55-65.
- Downloaded
- Viewed
Abstract
Objectives: This study aimed to evaluate the toxicity of CP pharmacopunture using bacterial reverse mutation test. Methods: To determine the mutagenic potential of CP pharmacopunture, histidine requiring Salmonella typhimurium (TA98, TA100, TA1535, and TA1537) and tryptophan requiring Escherichia coli (WP2uvrA, pKM101) strains were used. The negative (normal saline solution) and positive (Sodium azide, 2-Nitrofluorene, 2-Aminoanthracene, 9-Aminoacridine, and 4-Nitroquinoline N-oxide) control groups were used. To determine the dose levels of the main study, a dose range-finding study was conducted. Results: As a results of the dose range-finding study, the growth inhibition by CP pharmacopunture was not evident at any dose levels in the absence and presence of metabolic activation. As a results of the main study, the mean number of revertant colonies was less than twice when compared to the negative control values at all dose levels of the CP pharmacopuncture in the presence and absence of metabolic activation, showing no dose-related increase. In the positive control group, the number of revertant colonies was markedly increased by more than twice when compared to the negative control group. Conclusion: According to the results of this study, CP pharmacopunture did not show any signs of mutagenic potential.
- keywords
- CP pharmacopunture, capsaicin, toxicity, bacterial reverse mutation test, acupuncture
Other articles from this issue
- Donguibogam-Based Pattern Diagnosis Using Natural Language Processing and Machine Learning
- A Study on Methods of Acupuncture Points Combination and Hierarchy Concept of Acupuncture Prescription(鍼 處方) in Korean Medicine(韓醫學).
- The association between sleep and weight loss among adult women with obesity administered with Gamitaeeumjowee-tang
- Analysis of Research Trends on Postpartum-women Healthcare : A Scoping Review
- Bacterial Reverse Mutation Test of CP pharmacopunture
- Usage of informed consent form for Bee-venom pharmacopuncture Therapy at korean medicine hospitals and Proposal for development of a standard informed consent form.
- A Literature Study on the Combination of acupoints of HANGYEOK and YEOLGYEOK in the Saam Acupuncture Method
- A Survey on the Educational Status of Basic Korean Medicine and Basic Medical Science in Colleges of Korean Medicine in 2020
- Exploring the Ways to Apply Korean Traditional Medical Practices to the International Classification of Health Interventions through Focus Group Discussion
- Effects of Jeungmiobi-tang on the Articular Cartilage Injuries Induced by Monosodium Iodoacetate in Rats
- A Case Report on Multiple Rib Fracture Improved with Daewhangchija-paste Adhesive treatment and Herb-medicine treatment.
- Chronic Obstructive Pulmonary Disease Patients Treated with Korean Medicine Pulmonary Rehabilitation: Two case reports
- A Case Report of Hot Flush-Type Rosacea Improved by Baekho-tang
- A Case Report of Threatened Abortion And Placenta Previa Treated Twice With Korean Medical Hospitalization
- Chronic Pelvic Pain Patients with Gynecological Diseases Treated by Korean Medicine Treatment: Three Case Reports
- Benefit of chuna for managing symptoms in chronic fatigue syndrome patients: A systematic review and meta-analysis
- A Review of Clinical Research on Korean Medicine for Shoulder Pain Conducted in Korea
- A clinical literature review and research-trends analysis of bee venom pharmacopuncture for cancer patients
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.