The differential planetary gear reducer as a main component of the concrete mixer driving mechanism requires a strong torque to mix concrete compounds. As this component is currently dependent on imports, it is necessary to develop it by conducting a study on vibration analysis and the resonance problem. The noise and vibration of a concrete mixer reducer increase owing to the transmission error of planetary gears, and the damage of components occurs owing to the problems in design and production. In this study, the tooth-passing frequency is calculated to evaluate the noise and vibration of a mixer reducer, and a fast Fourier transform (FFT) analysis is conducted through a vibration test using an acceleration sensor. The vibration of the reducer is measured at three points of input and output of the shaft and planetary gear housing with fixed and variable revolutions per minute. The operating conditions of gears and bearings are evaluated by performing the FFT analysis, and the resonance problem is verified. The results show that No. 1 pinion and ring gears revolve disproportionately. The amplitude values appear high, and the wear of tooth faces occur in tooth-passing frequencies and harmonic components of No. 1 and No. 2 pinion-ring gears. Therefore, we conclude that design changes in the reducer and a correction of tooth profiles are required.