바로가기메뉴

본문 바로가기 주메뉴 바로가기

Muc5ac Gene Expression Induced by Cigarette Smoke is Mediated Via a Pathway Involving ERK1/2 and p38 MAPK

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2005, v.58 no.6, pp.590-599











  • Downloaded
  • Viewed

Abstract

keywords
Cigarette smoke, MUC5AC, MAPK, Signal transduction, Cigarette smoke, MUC5AC, MAPK, Signal transduction

Reference

1.

(1968) Site and nature of airway obstruction in chronic obstructive lung disease,

2.

(1984) Epidemiology of COPD:state of the art,

3.

(1984) Cigarette smoking and cardiovascular diseases,

4.

(1988) Pathobiological effects of acrolein in cultured human bronchial epithelial cells,

5.

(1960) The pathology of asthma,with special reference to changes in the bronchial mucosa,

6.

(1989) Airway mucus,

7.

(1994) Airway goblet cells:responsive and ada ptable front-line defenders,

8.

(1997) Airway mucosa: secretory cells, mucus and mucin genes,

9.

(1979) Hypersecretion of mucus glycoproteins in rat airways induced by tobacco smoke,

10.

(1986) Chemical constituents and bioactivity of tobacco smoke,

11.

(2002) Mucin apoprotein expression in COPD,

12.

(1996) Muc5ac,but not MUC2,is a prominent mucin in respiratory secretions,

13.

(2000) Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways,

14.

(1999) Epidermal growth factor system regulates mucin production in airways,

15.

(2001) Role of epidermal growth factor receptor activation in regulating mucin synthesis,

16.

(1998) Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pse udomonas aeruginosa-induced mucin overproduction in epithelial cells,

17.

(2002) Pseudomonas aeruginosa induces Muc5ac production via epidermal growth factor receptor,

18.

(2002) Induction of MUC2 and Muc5ac mucins by factors of the epidermal growth factor(EGF)family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1,

19.

(1998) Airway inflammation in young ma rijuana and tobacco smokers,

20.

(2001) Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke,

21.

(1999) Neutrophil elastase increases Muc5ac mRNA and protein expression in respiratory epithelial cells,

22.

(1999) Activation of the EGF receptor signaling pathway in human airway epithelial cells exposed to metals,

23.

(2000) Oxidative stress causes mucin synthesis via transactivation of epidermal growth fa ctor receptor:role of neutrophils,

24.

(2001) Mammalian MAP kinase signalling cascades,

25.

(1998) Acrolein-induced Muc5ac expression in rat airways,

26.

(1999) Regulation of human airway mucins by acrolein and inflammatory mediators,

27.

(1985) Depletion of nasal mucosal glutathione by acrolein and enhancement of formaldehyde-induced DNA-protein cross-linking by simultaneous exposure to acrolein,

Tuberculosis & Respiratory Diseases