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A Case of Cancer Associated Retinopathy with Small Cell Lung Carcinoma

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2005, v.59 no.6, pp.679-683









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Abstract

Cancer associated retinopathy (CAR) syndrome is a very rare ocular manifestation of paraneoplastic syndrome, and is characterized clinically by progressive visual impairment. Immune cross-reactivity between antigens in the cancerous tissue and antigens in the retina may play an important role in its pathogenesis, and most of cases are associated with lung carcinoma, particularly small cell lung cancer. The clinical triad of CAR is described as photosensitivity, ring scotomata, and an attenuated retinal arterial caliber. Here, we report a 61-year old male patient with CAR syndrome, who had small cell lung carcinoma in the stage of limited disease, with a brief review of the relevant literature. (Tuberc Respir Dis 2005; 59: 679-683)

keywords
Cancer associated retinopathy, CAR syndrome, Paraneoplastic syndrome, Small cell lung cancer, Cancer associated retinopathy, CAR syndrome, Paraneoplastic syndrome, Small cell lung cancer

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Tuberculosis & Respiratory Diseases