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Relation between ERCC1 Expression in Sputum and Survival after Cisplatin-Based Chemotherapy in Patients with Non-Small Cell Lung Cancer

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2006, v.60 no.2, pp.151-159







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Abstract

Background : Excision repair cross complementing gene 1 (ERCC1) not only has a protective role against carcinogens, but plays an important role in cisplatinresistance via the repair of cisplatinDNA adducts. This study investigated the association between the ERCC1 expression levels in sputum and survival after cisplatinbased chemotherapy in patients with inoperable nonsmall cell lung cancer (NSCLC).Methods : Using the sputum collected from 67 inoperable (stage

keywords
ERCC1, MAGE, Non‐small cell lung cancer, Sputum, ERCC1, MAGE, Non‐small cell lung cancer, Sputum

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Tuberculosis & Respiratory Diseases