Selection of Reference Equations for Lung Volumes and Diffusing Capacity in Korea

Background: The lung volume and diffusing capacity are influenced by ethnicity. However, there are no equations for predicting the normal lung volume in the adult Korean population, and there is only one equation for diffusing capacity. The aim of this study is to select the most suitable reference equation for the Korean population. Method: 30 men and 33 women at Hanyang University Guri Hospital, and 27 men and 34 women at Asan Medical Center in healthy nonsmoking adults were enrolled in this study. The subject’s age, gender, height, weight, lung volume by plethysmography, and diffusing capacity by a single breathing method were obtained. The most suitable equation with the lowest sum of residuals between the observed and predicted values for lung volume and diffusing capacity was selected. Result: At Hanyang University Guri Hospital, the equations with the lowest sum of residuals in the total lung capacity were ECSC’s equation in males (sum of residual: 0.04 L) and Crapo/Morris’s equation (-1.04) in women. At the Asan Medical Center, the equations with the lowest sum of residuals in the total lung capacity were Goldman/Becklake’s equation in males (sum of residual: -2.35) and the ECSC’s equation -4.49) in women. The equations with the lowest sum of residuals in the Diffusing capacity were Roca’s equation in males (sum of residual: -13.66 ml/min/mmHg) and Park’s in women (25.08) in Hanyang University Guri hospital and Park’s equation in all cases in the Asan Medical Center (male: -1.65 , female: -6.46). Conclusions: Until a reference equstion can be made for healthy Koreans by sampling, ECSC’s equation can be used for estimating the lung volume and Park’s can be used for estimating the diffusing capacity. (Tuberc Respir Dis 2006; 61: 218-226)

keywords: Reference equation, Lung volume, Diffusing capacity., Reference equation, Lung volume, Diffusing capacity.

Reference

(2005) Pulmonary function test, UUP

(1993) Lung volumes and forced ventilatory flows,

(1983) Standardization of lung function tests,

(1984) Subclinical effects of smoking,

(1999) Static lung volumes:reference values from a Latin population of Spanish descent,

(1979) Lung function in healthy British women,

(1972) Cigarette smoking and pulmonary diffusing capacity(Transfer factor),

(1975) Smoking and Pulmonary diffusing capacity,

(1976) Lung function changes in smokers with normal conventional spriometry,

10.

(1991) A review of the racial differences in the lung function of normal Caucasian,Chinese and Indian subjects,

11.

(1998) Normal predicted values of pulmonary function test in healthy Korean children,

12.

(1985) Normal predicted standards of single breath carbon monoxide diffusing capacity of lung in healthy nonsmoking adults,

13.

(1959) Respiratory function tests:normal values at median altitudes and the prediction of normal results,

14.

(1982) Lung volumes in healthy nonsmoking adults,

15.

(1961) Clinical usefuless of the single-breath pulmonary diffusing capacity test,

16.

(1981) Standardized single breath normal values for carbon monoxide diffusing capacity,

17.

(1985) Reference equations for the single- breath diffusing capacity:a cross-sectional analysis and effect of body size and age,

18.

(1995) Reference values for residual volume,functional residual capacity and total lung capacity,

19.

(2005) Standardisation of the single-breath determination of carbon monoxide uptake in the lung,

20.

(2005) Interpretative strategies for lung function tests,

21.

(1990) Single-breath carbon monoxide diffusing capacity prediction equations from a Mediterranean population,

22.

(2005) Normal predictive of spirometry in Korean population,

23.

(2006) Effect of a new spirometric reference equation on the interpretation of spirometric patterns and disease severity,

바로가기메뉴

Article Contents

Vol.61 No.3

Selection of Reference Equations for Lung Volumes and Diffusing Capacity in Korea

Abstract

Reference

Tuberculosis & Respiratory Diseases