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Risk Factors for Mortality in Community-Acquired Pneumonia Patients Admitted to a Referral Hospital

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2006, v.61 no.4, pp.347-355









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Abstract

Background: Pneumonia is the most common cause of death among infectious diseases with community-acquired pneumonia being the sixth leading cause of death in the USA. In Korea, several studies have evaluated the prognosis of community-acquired pneumonia with a limited number of patients and risk factors. This study, evaluated all the possible risk factors (including the pneumonia severity index; PSI) in for the community-acquired pneumonia patients admitted to a referral hospital. Methods: The medical records of patients admitted to the Chung-Aug University Yongsan Hospital between January 2002 and January 2005 for community-acquired pneumonia were reviewed retrospectively. The demographic data, comorbidity, radiographic findings and laboratory results which might influence the prognosis of pneumonia were analyzed. Results: Among 179 patients admitted for community-acquired pneumonia, 29 patients died (mortality 16%). The risk factors for mortality in the comorbidity category were congestive heart failure and a myocardial infarction. The laboratory data, showed that albumin, LDH, total cholesterol, HDL, PT, aPTT, hemoglobin and blood urea nitrogen (BUN) were related to the prognosis. For the pneumonia severity index, the mortality rate increased in a step-wise manner from class I through class V. Conclusions: Comorbidities such as congestive heart failure and myocardial infarction as well as the albumin, LDH, total cholesterol, HDL cholestreol, prothrombin time, activated partial thrombotin time, hemoglobin and blood urea nitrogen(BUN) are important risk factors for mortality in patients with community-acquired pneumonia. PSI is a valuable index for evaluating the prognosis of community-acquired pneumonia. (Tuberc Respir Dis 2006; 61: 347-355)

keywords
Community-acquired pneumonia, Risk factor, Mortality, PSI., Community-acquired pneumonia, Risk factor, Mortality, PSI.

Reference

1.

(2002) Clinical practice:management of community-acquired pneumonia,

2.

(1990) Severe community-acquired pneumonia:etiology,prognosis,and treatment,

3.

(1997) A prediction rule to identify low-risk patients with community-acquired pneumonia,

4.

(1985) Severe community-acquired pneumonia:factors influencing need of intensive care treatment and prognosis,

5.

(1987) Community-acquired pneumonia in adults in British hospitals in 1982-1983:a survey of aetiology,mortality,prognostic factors and outcome,

6.

(2004) The pattern and significance of abnormal liver function tests in community-acquired pneumonia,

7.

(1997) Laboratory abnormalities in patients with bacterial pneumonia,

8.

(2005) Factors associated with early death in patients with community-acquired pneumonia,

9.

(1997) Clinical characteristics and prognostic factors of severe community-acquired pneumonia,

10.

(1994) Clinical manifestation of patients dying of severe community acquired pneumonia,

11.

(2004) Adult community-acquired pneumonia in Malaysia:prediction of mortality from severity assessment on admission,

12.

(2000) Mortality and prognostic factors in patients with community-acquired pneumonia:an analysis of 231 cases,

13.

(2001) Causes and mechanisms of hypoalbuminaemia,

14.

(1986) Changes in plasma albumin concentration,synthesis rate,and mRNA level during acute inflammation,

15.

(1987) Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation,

16.

(2006) Serum HDL-C levels, log (TG/HDL-C) values and serum total cholesterol/ HDL-C ratios significantly correlate with radiological extent of disease in patients with community-acquired pneumonia,

17.

(2001) Initial risk class and length of hospital stay in community-acquired pneumonia,

18.

(2003) Intestinal protein loss and hypoalbuminemia in children with pneumonia,

19.

(2002) A child with severe pneumonia,pleural effusion and acute hypoalbuminemia,

20.

(1995) Hypoalbuminemia in hospitalized patients with community- acquired pneumonia,

21.

(2004) Human albumin solution for resuscitation and volume expansion in critically ill patients,

22.

(2000) Human albumin solution for resuscitation and volume expansion in critically ill patients,

23.

(2001) Patient survival after human albumin administration a meta-analysis of randomized, controlled trials,

24.

(1998) Human albumin administration in critically ill patients:systematic review of randomised controlled trials,

25.

(1996) Usefulness of lactate dehydrogenase and its isoenzymes as indicators of lung damage or inflammation,

26.

(1995) Community-acquired pneumonia in the intensive care unit,

27.

(1994) Initial investigation and treatment of the patient with severe community-acquired pneumonia,

28.

(1999) Processes and outcomes of care for patients with community-acquired pneumonia results from the Pneumonia Patient Outcomes Research Team(PORT) cohort study,

Tuberculosis & Respiratory Diseases