Lung Cancer Presented as Painful Swelling of Lower Legs

Trousseau's syndrome comsists of migratory thrombophlebitis and thromboembolic disorders of the venous and arterial systems in a malignancy or occult cancer. The overall incidence has been reported to vary from 1 to 11%. Pancreatic, lung, prostate, and stomach cancer is associated with the greatest risk of thromboembolic events. We encountered a 49-year-old man who presented with painful swelling of his lower legs. The chest radiograph showed increased opacity of the Left middle lung fields and Doppler sonography showed a thrombus in the left superficial femoral vein. Chest Computed Tomography showed a 5cm sized left hilar mass invading the pericardium with lymphadenopathy. The bronchoscope biopsy demonstrated an adenocarcinoma of the lung. Platinum based chemotherapy and anticoagulant therapy with warfarin was carried out. The patient was later discharged with an improvement in the painful swelling of his lower legs. (Tuberc Respir Dis 2006; 61: 398-402)

keywords: lung cancer, Trousseau's syndrome, lung cancer, Trousseau's syndrome

Reference

(1977) Diagnosis and management of disseminated intravascular coagulation,

(1994) Cancer and thrombosis,

(1977) Trousseau's syndrome and other manifestations of chronic disseminated coagulopathy in patient with neoplasms:clinical,pathologic,and therapeutic features,

(1992) Ischemic heart disease precipitated by occult cancer,

(2003) Cancer-associated thrombosis,

(1985) Trousseau's syndrome in the head and neck,

(1998) Renal adenocarcinoma with vena cava invasion:current status of its diagnosis and treatment using total segmentary cavecromy,

(2003) Markers of coagulation and angiogenesis in cancer-associated venous thromboembolism,

Effect of warfarin anticoagulation on survival in carcinoma of the lung final report of Vaterans Administration Cooperative Study #75,

10.

(1993) Trousseau's syndrome,

11.

(1995) Spontaneous preoperative internal jugular and subclavian vein thrombosis associated with an early stage synchronous ovarian/endometrial malignancy,

12.

(2003) Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer,

13.

(2000) Vitamin K antagonist or low-molecular-weight heparin for the longterm treatment of symptomatic venous thromboembolism,

바로가기메뉴

Article Contents

Vol.61 No.4

Lung Cancer Presented as Painful Swelling of Lower Legs

Abstract

Reference

Tuberculosis & Respiratory Diseases