Two Cases of Transfusion Related Acute Lung Injury

Transfusion related acute lung injury (TRALI) is a serious, potentially life-threatening complication of transfusion therapy that is sometimes under diagnosed and under reported. Patients with TRALI present with dyspnea/respiratory distress and fever. The symptoms, signs and chest radiological findings in TRALI are similar to transfusion associated circulatory overload, which makes it is difficult to distinguish it from circulatory overload. Although the mortality rate in cases of TRALI is relatively low, TRALI is the third most common cause of fatal transfusion reactions next to ABO blood type incompatibility and hepatitis. Mild-to-moderate cases of TRALI may be misdiagnosed as volume overload. Recently, we encountered two cases where the patients suffered from dyspnea and fever after a transfusion. and review of the relevant literature. (Tuberc Respir Dis 2006; 61: 473-478)

keywords: Blood transfusion, Pulmonary reaction, Acute lung injury, TRALI., Blood transfusion, Pulmonary reaction, Acute lung injury, TRALI.

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Article Contents

Vol.61 No.5

Two Cases of Transfusion Related Acute Lung Injury

Abstract

Reference

Tuberculosis & Respiratory Diseases