바로가기메뉴

본문 바로가기 주메뉴 바로가기

Tuberculosis & Respiratory Diseases

Article Contents

Prev
e-Submission

Vol.64 No.4
Citation Share

A Case of Adenocarcinoma Presenting a Solitary Pulmonary Nodule that Grows Slowly Over 10 Years

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.64 no.4, pp.318-323














& (2008). A Case of Adenocarcinoma Presenting a Solitary Pulmonary Nodule that Grows Slowly Over 10 Years. Tuberculosis & Respiratory Diseases, 64(4), 318-323.
  • Downloaded
  • Viewed
PDF Download

Abstract

It is difficult to distinguish a lung cancer from a pulmonary tuberculoma or other benign nodule. It is even more difficult to identify the type of lesion if the mass shows no change in size or demonstrates slow growth. Only a pathological confirmation can possibly reveal the nature of the lesion. A 61-year-old-woman was referred for a solitary pulmonary nodule. The nodule showed no change in size for the first two years and continued to grow slowly. Pathological and immunological analyses were conducted for confirmation of the nodule. The nodule was identified as a well-differentiated primary pulmonary adenocarcinoma. An LULobectomy was performed, and the post surgical stage of the nodule was IIIA (T2N2M0). Even though there are few risk factors, there is still the possibility of a malignancy in cases of non-growing or slow growing solitary pulmonary nodules. Therefore, pathological confirmation is encouraged to obtain a firm diagnosis.

keywords
Solitary pulmonary nodule, Slow growing lung cancer, Adenocarcinoma

Reference

1.

1. Ryu NS, Kim SJ, Kim SK, Lee KD, Kim JH, Cho DI,et al. Clinical study on lung cancer associated with pulmonary tuberculosis. Tuberc Respir Dis 1986;33:35-42.

2.

2. Jung TH. Diagnosis of lung cancer. Tuberc Respir Dis1990;37:337-47.

3.

3. Kho WJ, Kim CH, Jang SH, Lee JH, Yoo CG, Chung HS, et al. Diagnostic approach to the solitary pulmonary nodule: reappraisal of the traditional clinical parameters for differentiating malignant nodule from benign nodule. Tuberc Respir Dis 1996;43:500-18.

4.

4. Tan BB, Flaherty KR, Kazerooni EA, Iannettoni MD.The solitary pulmonary nodule. Chest 2003;123:89S-96S.

5.

5. Lillington GA. Management of solitary pulmonary nodules. Dis Mon 1991;37:271-318.

6.

6. Becker GL, Whitlock WL, Schaefer PS, Tenholder MF.The impact of thoracic computed tomography in clinically staged T1, N0, M0 chest lesions. Arch Intern Med1990;150:557-9.

7.

7. Yoon BK, Kim EJ, Kim DI, Lee KH, Ryu JS, Kwak SM,et al. A case of adenocarcinoma presenting a solitary pulmonary nodule that showed no growth over 4 years. Tuberc Respir Dis 2005;59:326-9.

8.

8. Midthun DE, Swensen SJ, Jett JR. Approach to the solitary pulmonary nodule. Mayo Clin Proc 1993;68:378-85.

9.

9. Remy-Jardin M, Remy J, Giraud F, Marquette CH.Pulmonary nodules: detection with thick-section spiral CT versus conventional CT. Radiology 1993;187:513-20.

10.

10. Collins VP, Loeffler RK, Tivey H. Observations on growth rates of human tumors. Am J Roentgenol Radium Ther Nucl Med 1956;76:988-1000.

11.

11. Sung DW. Radiological findings of lung cancer: focus on atypical pattern. Tuberc Respir Dis 2005;58:554-61.

12.

12. Erasmus JJ, Connolly JE, McAdams HP, Roggli VL.Solitary pulmonary nodules: Part I. morphologic evaluation for differentiaton of benign and malignant lesions. Radiographics 2000;20:43-58.

13.

13. Yankelevitz DF, Henschke CI. Does 2-year stability imply that pulmonary nodules are benign? AJR Am J Roentgenol 1997;168:325-8.

14.

14. Woodring JH, Stelling CB. Adenocarcinoma of the lung: a tumor with a changing pleomorphic character.AJR Am J Roentgenol 1983;140:657-64.

15.

15. Hollings N, Shaw P. Diagnostic imaging of lung cancer.Eur Respir J 2002;19:722-42.

16.

16. Gupta NC, Maloof J, Gunel E. Probability of malignancy in solitary pulmonary nodules using fluorine-18-FDG and PET. J Nucl Med 1996;37:943-8.

17.

17. Kim WJ, Yim JJ, Yoo CG, Kim YW, Shim YS, Han SK.Diagnositic efficacy of FDG-PET in solitary pulmonary nodule. Tuberc Respir Dis 1997;44:1263-70.

18.

18. Kim GS, Im SC, Go YC, Park GH, Ju JY, Jo GJ, et al.Utility of FDG-PET in solitary pulmonary nodules and the relationship between standardized uptake values of PET and serum glucose. Tuberc Respir Dis 2003;55:589-96.

19.

19. Ost D, Fein AM, Feinsilver SH. Clinical practice. The solitary pulmonary nodule. N Engl J Med 2003;348:2535-42.

20.

20. MacMahon H, Austin JH, Gamsu G, Herold CJ, Jett JR,Naidich DP, et al. Guidelines for management of small pulmonary solitary nodules detected on CT scans: a statement from the Fleischner Society. Radiology2005;237:395-400.

Tuberculosis & Respiratory Diseases

e-Submission OA Policy