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Tuberculosis & Respiratory Diseases

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Vol.65 No.3
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Health-related Quality of Life Measurement with St. George’s Respiratory Questionnaire in Post-tuberculous Destroyed Lung

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.65 no.3, pp.183-190





& (2008). Health-related Quality of Life Measurement with St. George’s Respiratory Questionnaire in Post-tuberculous Destroyed Lung. Tuberculosis & Respiratory Diseases, 65(3), 183-190.
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Abstract

Background: The control of active pulmonary tuberculosis is still an issue in community medicine. But there are also considerable needs for supportive management of symptomatic patients with post-tuberculous destroyed lung.Few studies have evaluated clinical characteristics and health-related quality of life in patients with post-tuberculous destroyed lung. Methods: We evaluated lung function, exercise tolerance, HRCT and health-related quality of life measurements using the Korean version of St. George’s Respiratory Questionnaire (SGRQ) in 22 patients with parenchymal damage to more than a half of one lung due to pulmonary tuberculosis. Results: In the pulmonary function test, mixed defects and obstructive defects were observed in 10 (45.0%) and 9 (40.9%) of patients, respectively. In the cardiopulmonary exercise test, the mean VO2max% predicted (39.0%±10.9%) and O2 pulse% predicted (61.3%±13.6%) were markedly decreased. In the SGRQ, the impact score (mean 27.8±18.5) was significantly lower than the symptom score (mean 53.9±20.9) or activity score (mean 50.8±27.3) (p＜0.05,p＜0.01). Cronbach’s alpha coefficient value for reliability was more than 0.7 for each subscale and total score. The total score showed a significant negative correlation with FEV1% predicted (r=−0.46, p＜0.05) and SaO2 (r=−0.60, p＜0.05). On HRCT, a median of 9 (range 5∼15) bronchopulmonary segments were destroyed by less than half, which significantly correlated with SGRQ total score (r=−0.52, p=0.02). Conclusion: The reliability and validity of the Korean version of the SGRQ was acceptable for the measurement of health-related quality of life in patients with post-tuberculous destroyed lung.

keywords
Tuberculosis, Quality of life, Pulmonary function test

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