Recurrent Desquamative Interstitial Pneumonia with Fibrotic Lung Disease

Desquamative interstitial pneumonia is an uncommon form of interstitial lung diseases and it has a good prognosis compared with other types of idiopathic interstitial pneumonia. A 69-year old man was admitted to our hospital because of a 3-month history of dyspnea. The patient presented with hypoxemia. High-resolution computerized tomography of the patient showed ground glass opacity and traction bronchiectasis with subpleural early honeycombing on the both lung fields. The pathologic findings of the video-assisted thoracoscopy lung biopsy were compatible with desquamative interstitial pneumonia, and irregularly distributed interstitial fibrosis and inflammation were observed at the peripheral parenchyme. Oral predinsolone was started; his symptoms and chest x-ray were improved, and so he stopped taking the prednisolone. Ten months later, the desquamative interstitial pneumonia recurred. We report here on a case of recurrent desquamative interstitial pneumonia with fibrotic lung disease

keywords: Desquamative interstitial pneumonia, Recurrent, Fibrotic lung disease

Reference

1. Liebow AA, Steer A, Billingsley JG. Desquamative interstitial pneumonia. Am J Med 1965;39:369-404.

2. Carrington CB, Gaensler EA, Coutu RE, Fitzgerald MX, Gupta RG. Usual and desquamative interstitial pneumonia. Chest 1976;69:261-3.

3. Hartman TE, Primack SL, Kang EY, Swensen SJ, Hansell DM, McGuinness G, et al. Disease progression in usual interstitial pneumonia compared with desquamative interstitial pneumonia: assessment with serial CT. Chest 1996;110:378-82.

4. Tubbs RR, Benjamin SP, Reich NE, McCormack LJ, Van Ordstrand HS. Desquamative interstitial pneumonitis: cellular phase of fibrosing alveolitis. Chest 1977;72:159-65.

5. Akira M, Yamamoto S, Hara H, Sakatani M, Ueda E. Serial computed tomographic evaluation in desquamative interstitial pneumonia. Thorax 1997;52:333-7.

6. Bjoraker JA, Ryu JH, Edwin MK, Myers JL, Tazelaar HD, Schroeder DR, et al. Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1998;157:199-203.

7. Davies G, Wells AU, du Bois RM. Respiratory bronchiolitis associated with interstitial lung disease and desquamative interstitial pneumonia. Clin Chest Med 2004;25:717-26.

8. Kawabata Y, Takemura T, Hebisawa A, Ogura T, Yamaguchi T, Kuriyama T, et al. Eosinophilia in bronchoalveolar lavage fluid and architectural destruction are features of desquamative interstitial pneumonia. Histopathology 2008;52:194-202.

9. Hartman TE, Primack SL, Swensen SJ, Hansell D, McGuinness G, Müller NL. Desquamative interstitial pneumonia: thin-section CT findings in 22 patients. Radiology 1993;187:787-90.

10.

10. Carrington CB, Gaensler EA, Coutu RE, FitzGerald MX, Gupta RG. Natural history and treated course of usual and desquamative interstitial pneumonia. N Engl J Med 1978;298:801-9.

11.

11. Lipworth B, Woodcock A, Addis B, Turner-Warwick M. Late relapse of desquamative interstitial pneumonia. Am Rev Respir Dis 1987;136:1253-5.

12.

12. Chung JK, Kang HM, Kim KY, Han YC. A case of desquamative interstitial pneumonia. Korean J Med 1981;24:244-50.

13.

13. Kondoh Y, Taniguchi H, Kawabata Y, Yokoi T, Suzuki K, Takagi K. Acute exacerbation in idiopathic pulmonary fibrosis: analysis of clinical and pathologic findings in three cases. Chest 1993;103:1808-12.

14.

14. Collard HR, Moore BB, Flaherty KR, Brown KK, Kaner RJ, King TE Jr, et al. Acute exacerbations of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2007;176:636-43.

15.

15. Kim DS, Park JH, Park BK, Lee JS, Nicholson AG, Colby T. Acute exacerbation of idiopathic pulmonary fibrosis: frequency and clinical features. Eur Respir J 2006;27:143-50.

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Article Contents

Vol.65 No.4

Recurrent Desquamative Interstitial Pneumonia with Fibrotic Lung Disease

Abstract

Reference

Tuberculosis & Respiratory Diseases