A Case of Primary Localized Laryngo-tracheobronchial Amyloidosis

We report on a case of a patient with laryngo-tracheobronchial amyloidosis who complained of cough, sputum,and hoarseness. A chest X-ray showed consolidation in the right middle lobe. A chest CT scan showed diffuse,irregular narrowing of the tracheobronchial tree and atelectasis of the right middle lobe, with calcification of bronchial wall. Bronchoscopic findings were multinodular submucosal thickening of the right vocal cord, and yellowish multinodular submucosal thickening from the lower trachea through both main bronchi, as well as the lingular division of the left upper lobe, the right middle lobe, and the right lower lobe. The right middle lobe bronchus was nearly obstructed. The diagnosis of amyloidosis was made by multiple bronchoscopic biopsies on the right vocal cord and both bronchi. Pathologic findings were characteristic apple-green birefringence under polarized microscopy with Congo-red stain. The patient had no evidence of systemic amyloidosis. The patient is under conservative symptomatic treatment

keywords: Tracheobronchial amyloidosis, Laryngeal amyloidosis, Right middle lobe syndrome, Hoarseness

Reference

Utz JP, (1996) Pulmonary amyloidosis: the Mayo Clinic experience from 1980 to 1993, Ann Intern Med

Gibbaoui H, (2004) A case of primary diffuse tracheobronchial amyloidosis, Ann Thorac Surg

Kwon SW, (1993) A case of tracheo-bronchial amyloidosis, Korean J Med

Gillmore JD, (1999) Hawkins PN. Amyloidosis and the respiratory tract, Thorax

Yamamoto T, (2001) Primary diffuse tracheobronchial amyloidosis: radiologic findings, J Thorac Imaging

Dahl KA, (2004) Vannatta TL, Karwal MW, Thomas KW, Schraith DF. Tracheobronchial amyloidosis: a surgical disease with long-term consequences, J Thorac Cardiovasc Surg

Kurtz KA, (2003) Pathologic quiz case: a 49-year-old man with chronic cough and a left lung hilar mass. Tracheobronchial amyloidosis, Arch Pathol Lab Med

Piazza C, (2003) Endoscopic management of laryngo- tracheobronchial amyloidosis: a series of 32 patients, Eur Arch Otorhinolaryngol

O'Regan A, (2000) Tracheobronchial amyloidosis: the Boston University experience from 1984 to 1999, Medicine (Baltimore)

10.

Cho CW, (1995) A case of pseudotumorial tracheabronchial amyloidosis, Korean J Med

11.

김미옥 ; 손장원 ; 양석철 ; 윤호주 ; 신동호 ; 박성수 ; 박문향, (2003) 레이저 소작술을 시행한 미만성 기관기관지 유전분증 1예, 대한내과학회지

12.

Kwak YG, (2002) A case of primary localized tracheobronchial amyloidosis, Turbec Respir Dis

13.

Shah PL, (2002) The importance of complete screening for amyloid fibril type and systemic disease in patients with a myloidosis in the respiratory tract, Sarcoidosis Vasc Diffuse Lung Dis

14.

Kim HJ, (1995) Treatment of diffuse tracheobronchial amyloidosis by repeated electrocautry under fiberoptic bronchoscopy, Turbec Respir Dis

15.

Monroe AT, (2004) Tracheobronchial amyloidosis: a case report of successful treatment with external beam radiation therapy, Chest

바로가기메뉴

Article Contents

Vol.65 No.6

A Case of Primary Localized Laryngo-tracheobronchial Amyloidosis

Abstract

Reference

Tuberculosis & Respiratory Diseases