바로가기메뉴

본문 바로가기 주메뉴 바로가기

Tuberculosis & Respiratory Diseases

Article Contents

Prev Next
e-Submission

Vol.66 No.2
Citation Share

A Case of Mediastinal Teratoma Associated with Elevated Tumor Marker in Chronic Empyema

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2009, v.66 no.2, pp.127-131









& (2009). A Case of Mediastinal Teratoma Associated with Elevated Tumor Marker in Chronic Empyema. Tuberculosis & Respiratory Diseases, 66(2), 127-131.
  • Downloaded
  • Viewed
PDF Download

Abstract

Most mediastinal teratomas are histologically well-differentiated tumors and benign. The majority of patients with a mediastinal teratoma are asymptomatic and their tumors are usually discovered incidentally on chest radiography. On rare occasions this tumor will rupture spontaneously into the adjacent organs. A 72-year-old female patient was admitted for dyspnea and she had a multiloculated pleural effusion in the left lung field. Although repeated pleural biopsy and pleural fluid cytology did not prove the presence of malignancy, we assumed that this was a malignant effusion because it revealed consistently high levels of carcinoembryonic antigen and carbohydrate antigen 19-9, and the chest CT scan did not show typical fat or bone density in the mass. Secondary infection and an uncontrolled septic condition due to pleural empyema finally compelled the patient to undergo a surgical operation. Mature teratoma was the final diagnosis and she has done well without recurrence for 2 months.

keywords
Teratoma, Pleural effusion, Carcinoembryonic antigen

Reference

1.

Duwe BV, Sterman DH, Musani AI. Tumors of the mediastinum. Chest 2005;128:2893-909.

2.

Kimura C, Kamiyoshihara M, Sakata K, Itoh H, Morishita Y. Mediastinal mature teratoma perforating into the lung with elevated serum carbohydrate antigen 19-9 (CA19-9) levels: report of a case. Kyobu Geka 2003;56:247-50.

3.

Ha ES, Hur GY, Jung KH, Lee SY, Jo WM, Lee SY, et al. Teratoma presenting as an unilateral mediastinal ma ss with contralateral pleural effusion. Tuberc Respir Dis 2006;60:347-52.

4.

Jeon JB, Hwan CC, Moon TH, Cho JW, Ryu JS, Kwak SM, et al. Spontaneuos rupture of mediastinal teratoma into adjacent tissue. Tuberc Respir Dis 1999;47:400-5.

5.

Lee TH, Lee SE, Baik JJ, Chung Y. A case of mediastinal teratoma complicated by spontaneous ruptured into pleural cavity. Tuberc Respir Dis 1999;47:265-71.

6.

Oomman A, Santhosham R, Vijayakumar C, Jayaraman S, Ramachandran P, Kumar S. Anterior mediastinal teratoma presenting as cardiac tamponade. Indian Heart J 2004;56:64-6.

7.

Pack HM, Kim ES, Kang JH, Jee HO. Anterior mediastinal teratoma which complicated empyema. Korean J Thorac Cardiovasc Surg 1988;21:535-40.

8.

Light RW. Clinical practice: pleural effusion. N Engl J Med 2002;346:1971-7.

9.

Poe RH, Israel RH, Utell MJ, Hall WJ, Greenblatt DW, Kallay MC. Sensitivity, specificity, and predictive values of closed pleural biopsy. Arch Intern Med 1984; 144:325-8.

10.

Gu P, Huang G, Chen Y, Zhu C, Yuan J, Sheng S. Diagnostic utility of pleural fluid carcinoembryonic antigen and CYFRA 21-1 in patients with pleural effusion: a systematic review and meta-analysis. J Clin Lab Anal 2007;21:398-405.

11.

Nagata K, Iwasaki Y, Nakanishi M, Natsuhara A, Harada H, Yokomura I, et al. A case of mediastinal teratoma with elevated serum tumor marker levels. Nihon Kokyuki Gakkai Zasshi 2002;40:50-4.

Tuberculosis & Respiratory Diseases

e-Submission OA Policy