Coccidioidomycosis is a fungal infection caused by the soil fungus, Coccidioides immitis, which is endemic to the south-western United States. However, the incidence of coccidioidomycosis has recently increased due to the increase in overseas travel to endemic areas. We report a case of pulmonary coccidioidomycosis diagnosed in an immunocompetent person. A 28-year-old female, who had lived in Phoenix, Arizona, USA for 2 years, was admitted for an evaluation of persistent cough with fever lasting for 2 weeks. The chest X-ray and Chest CT revealed multifocal patchy consolidation and ground-glass opacity in both lungs as well as multiple enlarged right hilar and paratracheal lymph nodes. A percutaneous needLe biopsy of the main mass-like consolidation confirmed mature spherules of Coccidioides immitis in lung tissue. Pulmonary coccidioidomycosis should be considered in patients presenting with persistent cough with fever and a history of travel to or immigration from an endemic area.
Kim JH, Kim MA, Yang SK, Choi TY, Kim CW, Kim KH. A case of coccidioidomycosis. Korean J Dermatol 1976;14:73-9.
Woo JH, Lee JS, Lee DW, Jin SY, Kim DW, Lee WG. A case of disseminated coccidioidomycosis. J Korean Med Sci 1996;11:258-64.
Han SY, Kim CH, Son KP, Kim JK, Byun HW, Kim YS, et al. A case of disseminated coccidioidomycosis involving lung and skin in patient with diabetes mellitus and iatrogenic cushings syndrome. Tuberc Respir Dis 2005;58;399-403.
Lim G, Woo J, Chung YT, Uh ST, Park CS. A case of pulmonary coccidiodomycosis. Tuberc Respir Dis 1990;37:440-4.
Yang HS, Lee J, Lim CM, Lee SD, Koh Y, Kim WS, et al. A case of coccidioidomycosis manifested as solitary pulmonary nodule. Tuberc Respir Dis 1999;46:266-72.
Shin JS, Lee IS, Shin C, Kim A. Pulmonary coccidioidomycosis diagnosed in an immigrant. Tuberc Respir Dis 2001;51:448-52.
Sinn DH, Kwon YS, Choi SY, Chang WI, Park MK, Han J, et al. A case of pulmonary coccidioidomycosis mimicking lung cancer. Korean J Med 2005:69:419-23.
Kim JH, Hur GY, Jung KH, Jung HC, Park DW, Lee SY, et al. Disseminated coccidioidomycosis presenting with miliary nodules. Tuberc Respir Dis 2006;60:97-101.
Lee JE, Kim HJ, Cho YJ, Joh JS, Han SK, Shim YS, et al. A case of pulmonary coccidioidomycosis that was misdiagnosed as tuberculoma and a review of the reported cases in Korea. Korean J Med 2007;72:S206-10.
Davies SF, Sarosi GA. Fungal infection of the lung. The big 3--histoplasmosis, blastomycosis, coccidioidomycosis. Postgrad Med 1983;73:242-51.
Chiller TM, Galgiani JN, Stevens DA. Coccidioidomycosis. Infect Dis Clin North Am 2003;17:41-57.
Galgiani JN. Coccidioidomycosis: a regional disease of national importance. Rethinking approaches for control. Ann Intern Med 1999;130:293-300.
Desai SA, Minai OA, Gordon SM, O’Neil B, Wiedemann HP, Arroliga AC. Coccidioidomycosis in non-endemic areas: a case series. Respir Med 2001;95:305-9.
Koepke A, Albus C, Barth A, Bernards P, Schütt- Gerowitt H, Allolio B. Coccidioidomycosis: differential diagnosis of lung infiltrates with peripheral eosinophilia. Dtsch Med Wochenschr 1989;114:218-21.
Kuipers S, Pannekoek BJ, Schellekens H. Pulmonary infection with Coccidioides immitis. Ned Tijdschr Geneeskd 1996;140:500-2.