Henoch-Schönlein purpura (HSP) is an immunologically mediated systemic vasculitis of small blood vessels that primarily involves the skin, gastrointestinal tract, joints and kidneys. HSP is a common vasculitic syndrome in children who, in most cases, achieve complete recovery. Pulmonary hemorrhage is a very rare manifestation of HSP. The authors present a case of a 46-year-old male presenting with pulmonary hemorrhage and renal involvement and the diagnosis of HSP. The patient responded to prednisolone therapy.
Levy M, Broyer M, Arsan A, Levy-Bentolila D, Habib R. Anaphylactoid purpura nephritis in childhood. Adv Nephrol Necker Hosp 1976;6:183-228.
Jacome AF. Pulmonary haemorrhage and death complicating anaphylactoid purpura. South Med J 1967;60:1003-4.
Roth DA, Wilz DR, Theil GB. Schönlein-Henoch syndrome in adults. Q J Med 1985;55:145-52.
Hoffman GS, Kerr GS, Leavitt RY, Hallahan CW, Lebovics RS, Travis WD, et al. Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med 1992;116:488-98.
Sullivan EJ, Hoffman GS. Pulmonary vasculitis. Clin Chest Med 1998;19:759-76.
Kelly WN, Harris ED Jr, Ruddy S, Sledge C. Textbook of rheumatology. 4th ed. Philadelphia: WB Saunders;1993.
Hall SL, Miller LC, Duggan E, Mauer SM, Beatty EC, Hellerstein S. Wegener granulomatosis in pediatric patients. J Pediatr 1985;106:739-44.
Paller AS, Kelly K, Sethi R. Pulmonary hemorrhage: an often fatal complication of Henoch-Schönlein purpura. Pediatr Dermatol 1997;14:299-302.
Kathuria S, Cheifec G. Fatal pulmonary Henoch-Schönlein syndrome. Chest 1982;82:654-6.
Weiss VF, Naidu S. Fatal pulmonary hemorrhage in Henoch-Schönlein purpura. Cutis 1979;23:687-8.
Markus HS, Clark JV. Pulmonary haemorrhage in Henoch- Schönlein purpura. Thorax 1989;44:525-6.
Saulsbury FT. Henoch - Schönlein purpura in children: report of 100 patients and review of the literature. Medicine (Baltimore) 1999;78:395-409.