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A Case of Bronchiolitis Interstitial Pneumonitis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2009, v.67 no.4, pp.364-368













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Abstract

Bronchiolitis interstitial pneumonitis (BIP), an unclassified and newly described interstitial pneumonia, has a combined feature of prominent bronchiolitis, interstitial inflammation, and fibrosis. It is distinct from bronchiolitis obliterans or bronchiolitis obliterans organizing pneumonia (BOOP). BIP has a better prognosis than common cases of interstitial pneumonia. However, BIP has a poorer prognosis than BOOP. BIP’s response to corticosteroids is not as successful as BOOP’s response to this treatment. We encountered the case of a 31-year-old woman withBIP with an initial presentation of dyspnea and a cough that had lasted for 3 months. The patient’s chest CT scan demonstrated patchy ground glass opacities and multiple ill-defined centrilobular nodules in both lungs,suggesting military tuberculosis or nontuberculous mycobacterial infection. A video-assisted thoracoscopic lung biopsy resulted in the diagnosis of BIP. Clinical symptoms, pulmonary lesions, and pulmonary function tests wereimproved after oral glucocorticoid therapy.

keywords
Interstitial lung diseases, Bronchiolitis, Bronchiolitis obliterans

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Tuberculosis & Respiratory Diseases