바로가기메뉴

본문 바로가기 주메뉴 바로가기

Tuberculosis & Respiratory Diseases

Article Contents

Prev Next
e-Submission

Vol.69 No.4
Citation Share

Depressive Conditions in Relation to Asthma Severity and Control

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2010, v.69 no.4, pp.265-270













& (2010). Depressive Conditions in Relation to Asthma Severity and Control. Tuberculosis & Respiratory Diseases, 69(4), 265-270.
  • Downloaded
  • Viewed
PDF Download

Abstract

Background: Psychological factors are increasingly recognized for their influence on the course of asthma, on a worldwide basis. The aim of this study was to assess the presence of depression, anxiety, and asthma-related quality of life in patients with asthma and to evaluate their impact on severity and control of asthma. Methods: We assessed the severity of asthma by comparing patients’ current medications to GINA guideline. The patients were classified into the controlled group (asthma patients with controlled disease) or into the uncontrolled group (asthma patients with uncontrolled disease), which included partly controlled and uncontrolled patients, again based on GINA guideline 2004. Patient-reported depressive symptoms, anxiety, and asthma-related quality of life were evaluated using the Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI), and Korean asthma quality of life (KAQLQ). Results: One hundred and twenty patients were enrolled (mean age, 55±1 years; 65% women). Among the 120 patients, 14 (12%) patients were classified as having mild asthma, 88 (73%) as having moderate asthma, and 18 (15%) as having severe asthma. Eighty-one (67%) of the 120 patients were controlled. The asthma-related quality of life showed the difference according to severity of asthma (p=0.002). The prevalence of depression was lower (10% vs 26%, p=0.024) and the asthma-related quality of life was higher (59.951 (29∼75) vs 35.103 (18∼72), p≤0.001) in the controlled group. Higher trait anxiety score and lower asthma-related quality of life were associated with depression (p＜0.001, p=0.002, respectively). Conclusion: Psychological factors, such as anxiety and depression, are strongly associated with asthma control. Therefore, screening and management of depression is needed in patients with asthma.

keywords
Asthma, Depression, Anxiety

Reference

1.

1. Cho SH, Park HW, Rosenberg DM The current status of asthma in Korea. J Korean Med Sci 2006;21:181-7.

2.

2. Global Initiative for Asthma (GINA). 2006 revision:global strategy for asthma management and prevention [Internet]. GINA; 2006 [cited 2010 Oct 14]. Available from: http://ginasthma.org.

3.

3. Kim DI, Kwon HS, Song WJ, Lee SM, Kim SH, Sohn SW, et al. Characteristics of the elderly asthma. J Asthma Allergy Clin Immunol 2008;28:98-104.

4.

4. Ryu YJ, Chun EM, Sim YS, Lee JH. Depression and anxiety in outpatients with chronic obstructive pulmonary disease. Tuberc Respir Dis 2007;62:11-8.

5.

5. Oraka E, King ME, Callahan DB. Asthma and serious psychological distress: prevalence and risk factors among US adults, 2001-2007. Chest 2010;137:609-16.

6.

6. Strine TW, Mokdad AH, Balluz LS, Berry JT, Gonzalez O. Impact of depression and anxiety on quality of life,health behaviors, and asthma control among adults in the United States with asthma, 2006. J Asthma 2008;45:123-33.

7.

7. Hahn HM, Yum TH, Shin YW, Kim KH, Yoon DJ,Chung KJ. A standardization study of Beck depression inventory in Korea. J Korean Neuropsychiatr Assoc 1986;25:487-502.

8.

8. Spielberger CD, Gorsuch RL, Lushene RE. Manual for the State-Trait Anxiety Inventory (Form X). Palo Alto:Consulting Psychologists Press; 1970.

9.

9. Park JW, Cho YS, Lee SY, Nahm DH, Kim YK, Kim DK, et al. Multi-center study for the utilization of quality of life questionnaire for adult Korean asthmatics (QLQAKA). J Asthma Allergy Clin Immunol 2000;20:467-80.

10.

10. Moy ML, Israel E, Weiss ST, Juniper EF, Dubé L,Drazen JM, et al. Clinical predictors of health-related quality of life depend on asthma severity. Am J Respir Crit Care Med 2001;163:924-9.

11.

11. Vollmer WM, Markson LE, O'Connor E, Sanocki LL,Fitterman L, Berger M, et al. Association of asthma control with health care utilization and quality of life.Am J Respir Crit Care Med 1999;160:1647-52.

12.

12. Kwon HS, Lee SH, Yang MS, Lee SM, Kim SH, Kim DI, et al. Correlation between the Korean version of asthma control test and health-related quality of life in adult asthmatics. J Korean Med Sci 2008;23:621-7.

13.

13. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-31.

14.

14. Korea Pharmaceutical Manufacturers Association. Drug market statistics in 2004 [Internet]. Seoul: Korea Pharmaceutical Manufactures Association; c2009 [cited 2005 Jan 23]. Available from: http://www.kpma.or.kr

15.

15. Ryu YJ, Chun EM, Lee JH, Chang JH. Prevalence of depression and anxiety in outpatients with chronic airway lung disease. Korean J Intern Med 2010;25:51-7.

16.

16. Yohannes AM, Baldwin RC, Connolly MJ. Depression and anxiety in elderly outpatients with chronic obstructive pulmonary disease: prevalence, and validation of the BASDEC screening questionnaire. Int J Geriatr Psychiatry 2000;15:1090-6.

17.

17. Goldney RD, Ruffin R, Fisher LJ, Wilson DH. Asthma symptoms associated with depression and lower quality of life: a population survey. Med J Aust 2003;178:437-41.

18.

18. Opolski M, Wilson I. Asthma and depression: a pragmatic review of the literature and recommendations for future research. Clin Pract Epidemiol Ment Health 2005;1:18.

19.

19. Chun TH, Weitzen SH, Fritz GK. The asthma/mental health nexus in a population-based sample of the United States. Chest 2008;134:1176-82.

20.

20. Yellowlees PM, Kalucy RS. Psychobiological aspects of asthma and the consequent research implications.Chest 1990;97:628-34.

21.

21. Moy ML, Israel E, Weiss ST, Juniper EF, Dubé L,Drazen JM, et al. Clinical predictors of health-related quality of life depend on asthma severity. Am J Respir Crit Care Med 2001;163:924-9.

22.

22. Dean BB, Calimlim BM, Kindermann SL, Khandker RK,Tinkelman D. The impact of uncontrolled asthma on absenteeism and health-related quality of life. J Asthma 2009;46:861-6.

23.

23. Mancuso CA, Peterson MG, Charlson ME. Effects of depressive symptoms on health-related quality of life in asthma patients. J Gen Intern Med 2000;15:301-10.

24.

24. Deshmukh VM, Toelle BG, Usherwood T, O'Grady B,Jenkins CR. The association of comorbid anxiety and depression with asthma-related quality of life and symptom perception in adults. Respirology 2008;13:695-702.

25.

25. Kim JT, Shin DK. A Study based on the standardization of the STAI for Korea. New Med J 1978;21:69-75.

26.

26. Mancuso CA, Wenderoth S, Westermann H, Choi TN,Briggs WM, Charlson ME. Patient-reported and physician-reported depressive conditions in relation to asthma severity and control. Chest 2008;133:1142-8.

Tuberculosis & Respiratory Diseases

e-Submission OA Policy