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A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2012, v.73 no.2, pp.115-121
Ki Hoon Park (The Catholic University of Korea School of Medicine)





Ji-Won Min (The Catholic University of Korea School of Medicine)
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Abstract

Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic pulmonary lymphoproliferative disorder, such as lymphocytic interstitial pneumonitis (LIP). A recent estimate predicts that less than 5% of LIP patients acquire malignant, low-grade, B-cell lymphoma. In Korea, there has been no previous report of malignant low-grade, B-cell lymphoma, acquired from LIP. Here, we present the case of a patient with LIP that developed into pulmonary MALT lymphoma, six years after diagnosis.

keywords
Lymphoma, Lymphoproliferative Disorders, Lung Diseases, Interstitial, Lymphoid Tissue

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Tuberculosis & Respiratory Diseases