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Pulmonary Cryptococcosis Mimicking Primary Lung Cancer with Multiple Lung Metastases

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2012, v.73 no.3, pp.182-186
https://doi.org/10.4046/trd.2012.73.3.182
Yu Seung Kim (Catholic University of Korea)

In Hee Lee (The Catholic University of Korea College of Medicine)
Hyun Seon Kim (The Catholic University of Korea College of Medicine)
Su Sin Jin (The Catholic University of Korea College of Medicine)
Jong Hwan Lee (The Catholic University of Korea College of Medicine)
Sung-Kyoung Kim (The Catholic University of Korea College of Medicine)
So Hyang Song (The Catholic University of Korea College of Medicine)
Jinyoung Yoo (The Catholic University of Korea College of Medicine)

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Abstract

Cryptococcosis is an invasive fungal infection, which is more common in immunocompromised patients. However, pulmonary cryptococcosis can occur in immunocompetent patients and should be considered on a differential diagnosis for nodular or mass-like lesions in chest radiograph. Recently, we experienced a patient with pulmonary cryptococcosis, successfully treated with oral fluconazole therapy. A 74-year-old female patient was referred for an evaluation of abnormal images, a large consolidative mass with multiple nodular consolidations and small nodules that mimics primary lung cancer with multiple lung to lung metastases. Computed tomography-guided lung biopsy confirmed the diagnosis of pulmonary cryptococcosis. The follow-up image taken after 4 months with oral fluconazole treatment showed marked improvement.

keywords
Cryptococcosis, Lung Neoplasms, Multiple Pulmonary Nodules

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Tuberculosis & Respiratory Diseases