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Tuberculosis & Respiratory Diseases

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Vol.77 No.1
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A Case of Lung Carcinoma with Rhabdoid Phenotype Mimicking an Aspergilloma in Patient with Recurrent Hemoptysis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2014, v.77 no.1, pp.38-41







& (2014). A Case of Lung Carcinoma with Rhabdoid Phenotype Mimicking an Aspergilloma in Patient with Recurrent Hemoptysis. Tuberculosis & Respiratory Diseases, 77(1), 38-41.
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Abstract

Malignant rhabdoid tumor was first discovered in the kidney, and rhabdoid tumor of the lung was first reported in 1995. These were included as the variants of large-cell carcinoma, according to the 1999 World Health Organization classification of lung tumors. The rhabdoid tumor of the lung exhibits aggressive biological behavior and has a poor prognosis, and only a few reports of this tumor exist. We report a case of lung carcinoma with a rhabdoid phenotype, initially misdiagnosed as an aspergilloma, in a 48-year-old man who presented with recurrent hemoptysis. The chest computed tomography scans showed a huge consolidative lesion with an air crescent sign in the left upper lung and no contrast-enhancing lesion. An aspergilloma was diagnosed by the radiologist. However, after surgical excision and pathological examination, rhabdoid carcinoma was diagnosed. A surgical resection helps to make it possible to pathologically distinguish a malignancy from an aspergilloma.

keywords
Rhabdoid Tumor, Hemoptysis, Aspergillosis

Reference

1.

1. Beckwith JB, Palmer NF. Histopathology and prognosis of Wilms tumors: results from the First National Wilms’ Tumor Study. Cancer 1978;41:1937-48.

2.

2. Colby TV, Koss MN, Travis WD. Tumors of the lower respiratory tract. Atlas of tumor pathology. Fascicle 13. Washington, DC: AFIP; 1995. p. 311.

3.

3. Travis WD, Colby TV, Corrin B, Shimosato Y, Brambilla E. Histological typing of the lung and pleural tumours. Berlin:Springer-Verlag; 1999. p. 40-2.

4.

4. Tamboli P, Toprani TH, Amin MB, Ro JS, Ordonez NG, Ayala AG, et al. Carcinoma of lung with rhabdoid features. Hum Pathol 2004;35:8-13.

5.

5. Parham DM, Weeks DA, Beckwith JB. The clinicopathologic spectrum of putative extrarenal rhabdoid tumors. An analysis of 42 cases studied with immunohistochemistry or electron microscopy. Am J Surg Pathol 1994;18:1010-29.

6.

6. Cavazza A, Colby TV, Tsokos M, Rush W, Travis WD. Lung tumors with a rhabdoid phenotype. Am J Clin Pathol 1996;105:182-8.

7.

7. Shimazaki H, Aida S, Sato M, Deguchi H, Ozeki Y, Tamai S. Lung carcinoma with rhabdoid cells: a clinicopathological study and survival analysis of 14 cases. Histopathology 2001;38:425-34.

8.

8. Saini G, Kumar M, Julka PK, Puri T, Sharma M, Rath GK. Rhabdoid variant of lung cancer: clinicopathological details of a case and a review of literature. J Cancer Res Ther 2009;5:54-7.

9.

9. Travis WD, Brambilla E, Muller-Hermlink HK, Harris CC. World Health Organization classification of tumors: pathology and genetics of tumors of the lung, pleura, thymus and heart. Lyon: IARC Press; 2004. p. 45-50.

10.

10. Haas JE, Palmer NF, Weinberg AG, Beckwith JB. Ultrastructure of malignant rhabdoid tumor of the kidney. A distinctive renal tumor of children. Hum Pathol 1981;12:646-57.

11.

11. Park Y, Kim TS, Yi CA, Cho EY, Kim H, Choi YS. Pulmonary cavitary mass containing a mural nodule: differential diagnosis between intracavitary aspergilloma and cavitating lung cancer on contrast-enhanced computed tomography. Clin Radiol 2007;62:227-32.

12.

12. Wu CY, Hu HY, Pu CY, Huang N, Shen HC, Li CP, et al. Pulmonary tuberculosis increases the risk of lung cancer: a population-based cohort study. Cancer 2011;117:618-24.

13.

13. Hiroshima K, Shibuya K, Shimamura F, Toyozaki T, Haga Y, Ohwada H, et al. Pulmonary large cell carcinoma with rhabdoid phenotype. Ultrastruct Pathol 2003;27:55-9.

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