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Vol.77 No.6
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The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2014, v.77 no.6, pp.251-257











& (2014). The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules. Tuberculosis & Respiratory Diseases, 77(6), 251-257.
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Abstract

Background: Transbronchial lung biopsy (TBLB) is a valuable diagnostic tool for peripheral pulmonary lesions. Thediagnostic yield of TBLB reportedly ranges from 41%–60%. Many studies demonstrated the various factors that influencethe yield of TBLB, including size, location, and distance from the carina or pleura. However, no study has evaluated theeffects of the bronchoscope diameter. We evaluated whether the bronchoscope diameter affected the diagnostic yield ofTBLB. Methods: We reviewed records from 178 patients who underwent TBLB using bronchoscopes of two different diameters(5.7 mm, thick outer diameter, Olympus BF-200; 4.9 mm, thin, BF-260). The fluoroscopic guidance rates, yield of TBLBand flexible bronchoscopy (FB) were compared between the two groups. Additionally, we compared the results of theprocedures with respect to diagnosis, distance from the pleura, and size of the lesion. Results: The results of fluoroscopic guidance, TBLB, and FB yield using thin diameter bronchoscope were significantlybetter than those obtained with a thick diameter bronchoscope (p=0.021, p=0.036, and p=0.010, respectively). Particularly,when the distance from the pleura was ≤ 10 mm, success rates for fluoroscopic guidance and FB with thin bronchoscopewere higher (p=0.013 and p=0.033, respectively), as compared to with thick bronchoscope. Conclusion: A thinner diameter bronchoscope increased the yield of bronchoscopy, and bronchial washing inconjunction with TBLB was useful in the diagnosis of peripheral pulmonary nodules.

keywords
Biopsy, Fine-Needle, Bronchoscopy, Lung Neoplasms, Bronchoscopy

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