바로가기메뉴

본문 바로가기 주메뉴 바로가기

Tuberculosis & Respiratory Diseases

Article Contents

Prev Next
e-Submission

Vol.80 No.1
Citation Share

Incidence of Fever Following Endobronchial Ultrasound–Guided Transbronchial Needle Aspiration

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2017, v.80 no.1, pp.45-51









& (2017). Incidence of Fever Following Endobronchial Ultrasound–Guided Transbronchial Needle Aspiration. Tuberculosis & Respiratory Diseases, 80(1), 45-51.
  • Downloaded
  • Viewed
PDF Download

Abstract

ackground: Endobronchial ultrasound–guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasivediagnostic method for mediastinal and hilar lymphadenopathy. This study aimed to investigate the incidence of feverfollowing EBUS-TBNA. Methods: A total of 684 patients who underwent EBUS-TBNA from May 2010 to July 2012 at Seoul National UniversityHospital were retrospectively reviewed. The patients were evaluated for fever by a physician every 6–8 hours during thefirst 24 hours following EBUS-TBNA. Fever was defined as an increase in axillary body temperature over 37.8oC. Results: Fever after EBUS-TBNA developed in 110 of 552 patients (20%). The median onset time and duration of feverwas 7 hours (range, 0.5–32 hours) after EBUS-TBNA and 7 hours (range, 1–52 hours), respectively, and the medianpeak body temperature was 38.3oC (range, 37.8–39.9oC). In most patients, fever subsided within 24 hours; however, sixcases (1.1%) developed fever lasting longer than 24 hours. Infectious complications developed in three cases (0.54%)(pneumonia, 2; mediastinal abscess, 1), and all three patients had diabetes mellitus. The number or location of sampledlymph nodes and necrosis of lymph node were not associated with fever after EBUS-TBNA. Multiple logistic regressionanalysis did not reveal any risk factors for developing fever after EBUS-TBNA. Conclusion: Fever is relatively common after EBUS-TBNA, but is transient in most patients. However, clinicians shouldbe aware of the possibility of infectious complications among patients with diabetes mellitus.

keywords
Endoscopic Ultrasound-Guided Fine Needle Aspiration, Fever, Infection

Reference

1.

1. Yasufuku K, Chiyo M, Sekine Y, Chhajed PN, Shibuya K, Iizasa T, et al. Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. Chest 2004;126:122-8.

2.

2. Gu P, Zhao YZ, Jiang LY, Zhang W, Xin Y, Han BH. Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis. Eur J Cancer 2009;45:1389-96.

3.

3. Adams K, Shah PL, Edmonds L, Lim E. Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer: systematic review and meta-analysis. Thorax 2009;64:757-62.

4.

4. Asano F, Aoe M, Ohsaki Y, Okada Y, Sasada S, Sato S, et al. Complications associated with endobronchial ultrasoundguided transbronchial needle aspiration: a nationwide survey by the Japan Society for Respiratory Endoscopy. Respir Res 2013;14:50.

5.

5. Caglayan B, Yilmaz A, Bilaceroglu S, Comert SS, Demirci NY, Salepci B. Complications of convex-probe endobronchial ultrasound-guided transbronchial needle aspiration: a multicenter retrospective study. Respir Care 2016;61:243-8.

6.

6. Leong SC, Marshall HM, Bint M, Yang IA, Bowman RV, Fong KM. Mediastinal abscess after endobronchial ultrasoundguided transbronchial needle aspiration: a case report and literature review. J Bronchology Interv Pulmonol 2013;20:338-41.

7.

7. Haas AR. Infectious complications from full extension endobronchial ultrasound transbronchial needle aspiration. Eur Respir J 2009;33:935-8.

8.

8. Lee HY, Kim J, Jo YS, Park YS. Bacterial pericarditis as a fatal complication after endobronchial ultrasound-guided transbronchial needle aspiration. Eur J Cardiothorac Surg 2015;48:630-2.

9.

9. Um SW, Choi CM, Lee CT, Kim YW, Han SK, Shim YS, et al. Prospective analysis of clinical characteristics and risk factors of postbronchoscopy fever. Chest 2004;125:945-52.

10.

10. Sharif-Kashani B, Shahabi P, Behzadnia N, Mohammad-Taheri Z, Mansouri D, Masjedi MR, et al. Incidence of fever and bacteriemia following flexible fiberoptic bronchoscopy: a prospective study. Acta Med Iran 2010;48:385-8.

11.

11. Kanemoto K, Satoh H, Ishikawa H, Ishikawa S, Ohtsuka M, Sekizawa K. Prospective study of fever and pneumonia after flexible fiberoptic bronchoscopy in older people. J Am Geriatr Soc 2006;54:827-30.

12.

12. Darjani HR, Kiani A, Bakhtiar M, Sheikhi N. Diagnostic yield of transbronchial needle aspiration (TBNA) for cases with intra-thoracic lymphadenopathies. Tanaffos 2011;10:43-8.

13.

13. Witte MC, Opal SM, Gilbert JG, Pluss JL, Thomas DA, Olsen JD, et al. Incidence of fever and bacteremia following transbronchial needle aspiration. Chest 1986;89:85-7.

14.

14. Eapen GA, Shah AM, Lei X, Jimenez CA, Morice RC, Yarmus L, et al. Complications, consequences, and practice patterns of endobronchial ultrasound-guided transbronchial needle aspiration:results of the AQuIRE registry. Chest 2013;143:1044-53.

15.

15. Pereira W, Kovnat DM, Khan MA, Iacovino JR, Spivack ML, Snider GL. Fever and pneumonia after flexible fiberoptic bronchoscopy. Am Rev Respir Dis 1975;112:59-64.

16.

16. Krause A, Hohberg B, Heine F, John M, Burmester GR, Witt C. Cytokines derived from alveolar macrophages induce fever after bronchoscopy and bronchoalveolar lavage. Am J Respir Crit Care Med 1997;155:1793-7.

17.

17. Steinfort DP, Johnson DF, Irving LB. Incidence of bacteraemia following endobronchial ultrasound-guided transbronchial needle aspiration. Eur Respir J 2010;36:28-32.

18.

18. Oguri T, Imai N, Imaizumi K, Elshazley M, Hashimoto I, Hashimoto N, et al. Febrile complications after endobronchial ultrasound-guided transbronchial needle aspiration for intrapulmonary mass lesions of lung cancer: a series of 3 cases. Respir Investig 2012;50:162-5.

19.

19. Huang CT, Chen CY, Ho CC, Yu CJ. A rare constellation of empyema, lung abscess, and mediastinal abscess as a complication of endobronchial ultrasound-guided transbronchial needle aspiration. Eur J Cardiothorac Surg 2011;40:264-5.

20.

20. Kouskov OS, Almeida FA, Eapen GA, Uzbeck M, Deffebach M. Mediastinal infection after ultrasound-guided needle aspiration. J Bronchology Interv Pulmonol 2010;17:338-41.

21.

21. Moffatt-Bruce SD, Ross P Jr. Mediastinal abscess after endobronchial ultrasound with transbronchial needle aspiration: a case report. J Cardiothorac Surg 2010;5:33.

22.

22. Ishimoto H, Yatera K, Uchimura K, Oda K, Takenaka M, Kawanami T, et al. A serious mediastinum abscess induced by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA): a case report and review of the literature. Intern Med 2015;54:2647-50.

23.

23. Fukunaga K, Kawashima S, Seto R, Nakagawa H, Yamaguchi M, Nakano Y. Mediastinitis and pericarditis after endobronchial ultrasound-guided transbronchial needle aspiration. Respirol Case Rep 2015;3:16-8.

Tuberculosis & Respiratory Diseases

e-Submission OA Policy