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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

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노봉방에서 추출된 카페인산 페네틸 에스테르가 함유된 한방화장품의 미백 개선에 관한 임상적 연구

A Clinical Research about Herbal Cosmetics Containing Caffeic acid phenethyl ester Isolated from Vespae Nidus on the Whitening Effects

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2017, v.38 no.3, pp.86-95
https://doi.org/10.13048/jkm.17027
차호열 (부산대학교 한방병원 한방소아과)
김희연 (부산대학교 한방병원 한방소아과)
하기태 (부산대학교)
천진홍 (부산대학교)
김기봉 (부산대학교)
차호열, 김희연, 하기태, 천진홍, & 김기봉. (2017). 노봉방에서 추출된 카페인산 페네틸 에스테르가 함유된 한방화장품의 미백 개선에 관한 임상적 연구. 대한한의학회지, 38(3), 86-95, https://doi.org/10.13048/jkm.17027
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Abstract

Objectives: The purpose of this clinical research was to investigate the effects of herbal cosmetics containing Caffeic acid phenethyl ester (CAPE), an ingredient compound of various herbs including Vespae Nidus, on the Whitening Effects. Methods: A total of 20 subjects who visited Pusan National University Hospital from March 2nd, 2017 to April 11th, 2017 were included. In this study, we evaluated the visual evaluation, the melanin index (M) and erythema index (E) through skin analysis equipment, the subjective whitening improvement analysis, and the adverse reaction according to product use. Statistical analysis was performed with independent t-test and Mann-Whitney’s U test. Statistical significance was achieved if the probability was less than 5% (p<0.05) Results: As a result of the visual evaluation, it was effective in improving skin whitening. The subjective whitening improvement analysis also showed positive results. However, no statistically significant differences were found between the test and control cosmetics in the melanin index (M) and erythema index (E) through skin analysis equipment. In the safety evaluation, some adverse reactions were reported, but no significant were observed directly from cosmetics. Conclusions: Considering the above results, we have confirmed the possibility of herbal cosmetics containing containing CAPE of Vespae Nidus Extracts.

keywords
Whitening, Herbal cosmetics, Caffeic acid phenethyl ester, Vespae Nidus, Propolis


참고문헌

1

1. Kim KY, Lee NK. Herbal Extracts Research Trend that have Effects on Melanin Production and Control. Kor J Aesthet Cosmetol. 2014;12(4):453-61.

2

2. Park JH, Lee MH. A Study of Skin Color by Melanin Index According to Site, Gestational Age, Birth Weight and Season of Birth in Korean Neonates. J Korean Med Sci. 2005;20(1):105–8.

3

3. Seo H, Seo GY, Ko SZ, Park YH. Inhibitory Effects of Ethanol Extracts from Polygoni multiflori radix and Cynanchi wilfordii radix on Melanogenesis in Melanoma Cells. J Korean Soc Food Sci Nutr. 2011;40:1086-91.

4

4. Seo EJ, Hong ES, Choi MH, Kim KS Lee SJ. Antioxidant and skin whitening effects of Ramnus yoshinoi extracts. Korean J Food Sci Technol. 2010;42:750-4.

5

5. Lew BL, Ryou JH, Lee Mh. The Anti -melanogenic Effect of Whitening Agent Containing Arbutin and β-Glucosidase. J Soc Cosmet Scientists Korea. 2004;30(3):415-8.

6

6. Jang JS, Jeong JC, Shin HC. Effects of Vespae Nidus on Peroxynitrite Production and Protein Expression of Proinflammatory Mediators. Korean J Oriental Physiology & Pathology. 2007;21(6):1499-505.

7

7. Murtaza G, Karim S, Akram MR, Khan SA, Azhar S, Mumtaz A, et al. Caffeic acid phenethyl ester and therapeutic potentials. Biomed Res Int. 2014;2014:145342.

8

8. Erdemli HK, Akyol S, Armutcu F, Akyol O. Antiviral properties of caffeic acid phenethyl ester and its potential application. J Intercult Ethnopharmacol. 2015;4(4):344-347.

9

9. Lee JY, Choi HJ, Chung TW, Kim CH, Jeong HS, Ha KT. Caffeic acid phenethyl ester inhibits alpha-melanocyte stimulating hormone -induced melanin synthesis through suppressing transactivation activity of microphthalmia -associated transcription factor. J Nat Prod. 2013;76(8):1399-405.

10

10. Jang DH, Yoo DY. Inhibitory Effect of Persimmon Leaves on Melanin Synthesis and its Action Mechanism in B16F10 cells. J Korean Obstetrics and Gynecology. 2009;22(2):43-59.

11

11. Jung HJ, Do EJ, Lee JS, Park HJ, Oh GS, Kim MR, et al. A Clinical Research about Herbal Cosmetics Containing Momordica charntia L. Extracts on the Anti-wrinkle and Whitening Effects. J Korean Med Ophthalmology and Otolaryngology and Dermatology. 2011;24(2):68-78.

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