- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Apply for Authority
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Effects of Jeungmiobi-tang on the Articular Cartilage Injuries Induced by Monosodium Iodoacetate in Rats
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2020, v.41 no.3, pp.138-151
&
(2020). Effects of Jeungmiobi-tang on the Articular Cartilage Injuries Induced by Monosodium Iodoacetate in Rats. Journal of Korean Medicine, 41(3), 138-151.
- Downloaded
- Viewed
Abstract
Objectives: This study was carried out to investigate the protective effects of Jeungmiobi-tang on the articular cartilage injuries induced by monosodium iodoacetate in rats. Methods: Twenty four rats were divided into three groups. Rats of normal group (n=8) were injected with 0.1 ml physiological saline into both knee joint cavities. In the rats of control group (n=8) and Jeungmiobi-tang group (n=8), Arthritis was induced by injecting with 0.1 ml monosodium iodoacetate (5 mg/ml) into both knee joint cavities. After the experiment, Gross and histopathological examinations on the knee joint were performed. The content of proteoglycan in articular cartilage and TNF-α and IL-1β in synovial fluid were also analyzed. Results: Grossly, Injuries to the articular cartilage surface was observed weak in the Jeungmiobi-tang group compared to the control group. Proteoglycan content in the articular cartilage was significantly higher in the Jeungmiobi-tang group than in the control group. The chondrocyte score was significantly lower in the Jeungmiobi-tang group than in the control group. Conclusion: According to these results, that Jeungmiobi-tang has protective effects on the articular cartilage injuries induced by monosodium iodoacetate in rats.
- keywords
- Jeungmiobi-tang, Monosodium iodoacetate, Articular cartilage injury, Proteoglycan. Osteoarthritis
Other articles from this issue
- Donguibogam-Based Pattern Diagnosis Using Natural Language Processing and Machine Learning
- A Study on Methods of Acupuncture Points Combination and Hierarchy Concept of Acupuncture Prescription(鍼 處方) in Korean Medicine(韓醫學).
- The association between sleep and weight loss among adult women with obesity administered with Gamitaeeumjowee-tang
- Analysis of Research Trends on Postpartum-women Healthcare : A Scoping Review
- Bacterial Reverse Mutation Test of CP pharmacopunture
- Usage of informed consent form for Bee-venom pharmacopuncture Therapy at korean medicine hospitals and Proposal for development of a standard informed consent form.
- A Literature Study on the Combination of acupoints of HANGYEOK and YEOLGYEOK in the Saam Acupuncture Method
- A Survey on the Educational Status of Basic Korean Medicine and Basic Medical Science in Colleges of Korean Medicine in 2020
- Exploring the Ways to Apply Korean Traditional Medical Practices to the International Classification of Health Interventions through Focus Group Discussion
- Effects of Jeungmiobi-tang on the Articular Cartilage Injuries Induced by Monosodium Iodoacetate in Rats
- A Case Report on Multiple Rib Fracture Improved with Daewhangchija-paste Adhesive treatment and Herb-medicine treatment.
- Chronic Obstructive Pulmonary Disease Patients Treated with Korean Medicine Pulmonary Rehabilitation: Two case reports
- A Case Report of Hot Flush-Type Rosacea Improved by Baekho-tang
- A Case Report of Threatened Abortion And Placenta Previa Treated Twice With Korean Medical Hospitalization
- Chronic Pelvic Pain Patients with Gynecological Diseases Treated by Korean Medicine Treatment: Three Case Reports
- Benefit of chuna for managing symptoms in chronic fatigue syndrome patients: A systematic review and meta-analysis
- A Review of Clinical Research on Korean Medicine for Shoulder Pain Conducted in Korea
- A clinical literature review and research-trends analysis of bee venom pharmacopuncture for cancer patients
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.