Article Detail

Home > Article Detail
  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

Improvement of Low Bone Mineral Density Treated with Jeopgol-tang in a Middle-Aged Man: A Case Report

Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2021, v.42 no.2, pp.90-97




  • Downloaded
  • Viewed

Abstract

Bone mineral density (BMD) is a major diagnostic marker for bone health. A 44-year-old male had BMD of 0.81 g/cm2 (Z-score: -3.1) in lumbar spine scan and 0.54 g/cm2 (Z-score: -2.7) for femoral neck from regular medical checkup in Apr 2020. He had no other specific medical conditions except hyperlipidemia and alcohol was a single risk factor for fracture according to Fracture Risk Assessment Tool. After he was diagnosed with liver-kidney deficiency and treated for 20 weeks with Jeopgol-tang originally patented for promoting fracture recovery, lumbar spine BMD increased by 13.6 % (0.92 g/cm2, Z-score: -2.1) and femoral neck BMD by 22.2% (0.66 g/cm2, Z-score: -1.8) compared with those of Mar 2020. Herbal medicine treatment for tonifying liver and kidney to improve BMD warrants further investigation.

keywords
Jeopgol-tang, osteoporosis, osteopenia, bone mineral density, bone health, FRAX, case report


Reference

1

1. Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med. 1993;94(6):646-50.

2

2. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1994;843:1-129.

3

3. Mauck KF, Clarke BL. Diagnosis, screening, prevention, and treatment of osteoporosis. Mayo Clin Proc. 2006;81(5):662-72.

4

4. Johnell O, Kanis JA, Odén A, Sernbo I, Redlund-Johnell I, Petterson C, De Laet C, Jönsson B. Mortality after osteoporotic fractures. Osteoporos Int. 2004 Jan;15(1):38-42.

5

5. Ha YC, Kim TY, Lee A, Lee YK, Kim HY, Kim JH, et al. Current trends and future projections of hip fracture in South Korea using nationwide claims data. Osteoporos Int. 2016;27(8):2603-9.

6

6. Kim J, Lee E, Kim S, Lee TJ. Economic Burden of Osteoporotic Fracture of the Elderly in South Korea: A National Survey. Value Health Reg Issues. 2016;9:36-41.

7

7. Kanis J. Assessment of osteoporosis at the primary health-care level. Technical Report:WHO Collaborating Centre, University of Sheffield; 2008 [cited Nov 2020]. Available from: http://www.shef.ac.uk/FRAX

8

8. Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, et al. Clinician's Guide to Prevention and Treatment of Osteoporosis. Osteoporos Int. 2014;25(10):2359-81.

9

9. Mikyas Y, Agodoa I, Yurgin N. A systematic review of osteoporosis medication adherence and osteoporosis-related fracture costs in men. Appl Health Econ Health Policy. 2014;12(3):267-77.

10

10. Zhao JG, Zeng XT, Wang J, Liu L. Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis. JAMA. 2017;318(24):2466-82.

11

11. Liu Y, Liu JP, Xia Y. Chinese herbal medicines for treating osteoporosis. Cochrane Database Syst Rev. 2014;(3):CD005467.

12

12. Yun G, Kang J, Lee H. Effects of Korean herbal medicine (Cheong-A-Won) for treatment of bone mineral density in women with osteoporosis: A randomized, double blind, placebo controlled trial. Eur J Integr Med. 2018;20:84-9.

13

13. Guide publishing group of Korean society for bone and mineral research. Physician's guide for osteoporosis. Seoul: Cdmthebig 2018.

14

14. Department of kidney internal medicine. Kidney Internal Medicine. Seoul: Gunjachulpansa 2015:116-20.

15

15. Lee H, Hahm D, Kim H, Sohn B, Hwang D, Choi Y, editors. The effect of Jeopgol-tang on recovery of bone fracture in Sprague-Dawley rats. The Annual Conference of Traditional Korean Medicine 2006.

16

16. Lee H, Hahm D, Kim H, Sohn B, Choi Y, DS H. Crude drugs composition for accelerating recovery of bone fracture. 10-0731160. 2007.

17

17. Leutner M, Matzhold C, Bellach L, Deischinger C, Harreiter J, Thurner S, et al. Diagnosis of osteoporosis in statin-treated patients is dose-dependent. Ann Rheum Dis. 2019;78(12):1706-11.

18

18. Hong S, You S. A study of prevalence and related risk factors of osteoporosis for employees. JKIECS 2013;8(4):631-7.

19

19. Han G, Kim S. What Cases Are Worth Publishing in the Korean Medical Case Report? Korean J Acupunct 2020;37(3):159-71.

20

20. Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D; CARE Group. The CARE guidelines: consensus-based clinical case reporting guideline development. J Med Case Rep. 2013;7:223.

21

21. Fitzpatrick LA. Secondary causes of osteoporosis. Mayo Clinic proceedings. 2002;77(5):453-68.

상단으로 이동

Journal of Korean Medicine