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A Case of Drug Induced Interstitial Pneumonitis by Gemcitabine

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2004, v.56 no.3, pp.315-320










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Abstract

Gemcitabine is an effective newly developed chemotherapeutic agent, which is increasingly being used to treat non-small cell lung, ovarian and breast cancers. Pulmonary toxicity is usually self-limiting mild dyspnea, bronchospasm, but severe pulmonary toxicity is rarely reported. Herein, we report drug induced interstitial lung disease associated with gemcitabine treatment. High resolution computerized tomogram (HRCT) showed an increased ground glass opacity and thickened septal lines. The patient showed a rapid good response with prednisolone treatment.(Tuberculosis and Respiratory Diseases 2004, 56:315-320)

keywords
Gemcitabine, Pulmonary infiltrates, Corticosteroid therapy, Gemcitabine, Pulmonary infiltrates, Corticosteroid therapy

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Tuberculosis & Respiratory Diseases