A Case of Primary Signet Ring Cell Carcinoma of Lung with Multiple Bone Metastasis

Signet ring cell carcinoma of lung is an unique variant of mucin producing adenocarcinoma which is characterized by abundant intracellular mucin accumulation. Only a few cases of primary signet ring cell carcinoma of lung have been reported in the world wide literature. And we have, recently experienced one case of primary signet ring cell carcinoma of lung. A 55 years old man was evaluated for paralysis of lower extremities and was found to have lung cancer in the left upper and lower lobe with pleural, multiple spinal, bone and liver metastases. Signet ring tumor cells were revealed by cytologic examination of pleural fluids. And there were no evidence of signet ring cell carcinoma of other organs. Primary signet ring cell carcinoma of lung seems to have an aggressive behavior and therapeutic modalities could be different from those for signet ring cell carcinomas from other organs. Therefore it is important to separate primary signet ring cell adenocarcinoma of lung from metastatic tumors. (Tuberc Respir Dis 2004; 57:594-598)

keywords: Signet ring cell carcinoma, Lung cancer.다발성 골전이를 동반한 진행된 원발성 반지세포 폐암종(Primary Signet Ring Cell Carcinoma of Lung) 1예아주대학교 의과대학 호흡기내과학교실, 1병리학교실신도현, 김형일, 임선교, 이승원, 정연무, 최영인, 신승수, 박주헌, 오윤정, 박광주, 황성철, 박래웅1, 심 철1A Case of Primary Signet Ring Cell Carcin

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Article Contents

Vol.57 No.6

A Case of Primary Signet Ring Cell Carcinoma of Lung with Multiple Bone Metastasis

Abstract

Reference

Tuberculosis & Respiratory Diseases