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Tuberculosis & Respiratory Diseases

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Vol.59 No.1
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Progressive Lung Involvement during Steroid Therapy in Idiopathic Hypereosinophilic Syndrome

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2005, v.59 no.1, pp.13-103














& (2005). Progressive Lung Involvement during Steroid Therapy in Idiopathic Hypereosinophilic Syndrome. Tuberculosis & Respiratory Diseases, 59(1), 13-103.
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Abstract

Hypereosinophilic syndrome (HES) is characterized by a sustained eosinophilia of 1,500/mm3 or more in the absence of any known causes or the signs and symptoms of organ involvement. We report a 64-year-old man with HES initially presenting with involvement of the liver and bone marrow. Despite controlling the eosinophilia by corticosteroid, he developed a cerebral infarction and later progressive interstitial pneumonia. Brain angiography revealed a severe stenosis of the proximal right internal carotid artery (ICA) and a complete obstruction of the intracranial ICA. An open lung biopsy revealed fibrosis and lymphoplasma cell infiltration without eosinophils, which were consistent with nonspecific interstitial pneumonia. (Tuberc Respir Dis 2005; 59: 97-103)

keywords
Idiopathic hypereosinphilic syndrome, Idiopathic hypereosinphilic syndrome

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