특발성 과호산구 증후군에서 스테로이드 투약 중 진행한 폐침윤 1례
Progressive Lung Involvement during Steroid Therapy in Idiopathic Hypereosinophilic Syndrome
이시내 (이화여자대학교)
김유경 (이화여자대학교)
이진화 (숭의여자대학)
장중현 (이화여자대학교)
정지향 (이화여자대학교)
천은미 (이화여자대학교)
최주영 (이화의대)
정지민 (이화의대)
심윤수 (이화의대)
변건우 (이화의대)
나윤주 (이화의대)
강민정 (이화의대)
강인숙 (이화의대)
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Abstract
Hypereosinophilic syndrome (HES) is characterized by a sustained eosinophilia of 1,500/mm3 or more in the absence of any known causes or the signs and symptoms of organ involvement. We report a 64-year-old man with HES initially presenting with involvement of the liver and bone marrow. Despite controlling the eosinophilia by corticosteroid, he developed a cerebral infarction and later progressive interstitial pneumonia. Brain angiography revealed a severe stenosis of the proximal right internal carotid artery (ICA) and a complete obstruction of the intracranial ICA. An open lung biopsy revealed fibrosis and lymphoplasma cell infiltration without eosinophils, which were consistent with nonspecific interstitial pneumonia. (Tuberc Respir Dis 2005; 59: 97-103)
- keywords
- Idiopathic hypereosinphilic syndrome, Idiopathic hypereosinphilic syndrome
참고문헌
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