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기관과 대장에 발생한 월발성 mucosa-associated lymphoid tissue 림프종 1예

A Case of Primary Mucosa-Associated Lymphoid Tissue Lymphoma of the Trachea and Colon

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2005, v.59 no.2, pp.193-197
배준용 (순천향대학교)
장안수 (순천향대학교)
백상현 (순천향대학교)
박재성 (순천향대학교)
고은석 (순천향대학교)
박춘식 (순천향대학교)
박성규 (순천향대학교)
나현식 (순천향대학교)
최재성 (순천향대학교)
최준호 (순천향대학교)
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초록

MALT 림프종은 안구, 침샘, 감상선, 폐, 위, 소장, 대장, 방광, 여성 생식기에 발생하며, 대부분이 단일 기관을 침범하고 국소 치료와 화학요법에 좋은 예후를 보인다. MALT 림프종이 기관을 침범하는 경우는 거의 보고된 경우가 없으며 국내에선 폐의 MALT 림프종이 보고된 적이 있었다15. 이에 저자 등은 기관과 대장에 발생한 원발성 MALT 림프종 1예를 문헌 고찰과 함께 보고하는 바이다.

keywords
Mucosa-associated lymphoid tissue, Trachea, Colon, Mucosa-associated lymphoid tissue, Trachea, Colon

Abstract

The 64-year-old female patient with cough and intermittent hemoptysis of six months duration visited our hospital. On chest computed tomography, a small, ovoid, 1.3cm sized and well enhanced lesion was detected on the distal trachea. Two multiple lobulated lesions on the sigmoid and transverse colon were revealed on the colonoscopy. The histological findings showed small and medium sized lymphocytes infiltration, CD20 and CD79a positive staining and multiple lymphoepithelial lesions on the distal trachea and colon tissues. Herein, a case of primary MALT lymphoma, with involvement of the trachea and colon, which was treated with rituximab (CD20 anti-monoclonal antibody), cyclophosphamide, adriamycin, vincristine and prednisolone (CHOP regimen), is reported. (Tuberc Respir Dis 2005; 59: 193-197)

keywords
Mucosa-associated lymphoid tissue, Trachea, Colon, Mucosa-associated lymphoid tissue, Trachea, Colon

참고문헌

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Tuberculosis & Respiratory Diseases