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Tuberculosis & Respiratory Diseases

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Vol.59 No.3
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결핵성 뇌수막염에 동반된 뇌성 염분소실증후군(Cerebral salt wasting syndrome) 1예

A Case of Cerebral Salt Wasting Syndrome Associated with Tuberculous Meningitis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2005, v.59 no.3, pp.306-310
이자영 (서울대학교)
이재영 (한림대학교)
모은경 (한림대학교)
박용범 (한림대학교)
임은주 (세계사이버대학)
김현규 (한림대학교)
김두만 (한림대학교)
이은실 (한림대학교)
이재형 (한림대학교)
김형수 (한림대학교)
장지선 (한림대학교)
이자영, 이재영, 모은경, 박용범, 임은주, 김현규, 김두만, 이은실, 이재형, 김형수, & 장지선. (2005). 결핵성 뇌수막염에 동반된 뇌성 염분소실증후군(Cerebral salt wasting syndrome) 1예. Tuberculosis & Respiratory Diseases, 59(3), 306-310.
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초록

저자들은 결핵성 뇌수막염을 가진 31세 남자환자에서 심한 다뇨와 저나트륨혈증, 저혈압, 요중 염분 소실이 동반되어 있어 CSWS로 진단하고 항결핵제 투여와 식염수, 염류코르티코이드의 투여 후 임상적 호전을 보인 증례 1예를 경험하였기에 보고하는 바이다.

keywords
Cerebral salt wasting syndrome, Tuberculous meningitis, Hyponatremia, Cerebral salt wasting syndrome, Tuberculous meningitis, Hyponatremia

Abstract

Hyponatremia which is due to excessive sodium loss in the urine and decrease in extracellular fluid volume following an acute or chronic central nervous system injury, has been conjunctively described as cerebral salt wasting syndrome (CSWS). This syndrome is often confused with dilutional hyponatremia due to inappropriate secretion of antidiuretic hormone. Accurate diagnosis and management are mandatory for improvement of the course of the disease. This report describes a case of a 31-year-old male patient with CSWS associated with tuberculous meningitis. The patient exhibited hyponatremia, polyuria, excessive natriuresis, volume depletion, and hypotension. He was diagnosed to manifest CSWS and was treated by administration of fluids, salt, and fludrocortisone. After the respective treatments, symptoms of polyuria and hypotension were gradually resolved and hyponatremia was corrected. (Tuberc Respir Dis 2005; 59: 306-310)

keywords
Cerebral salt wasting syndrome, Tuberculous meningitis, Hyponatremia, Cerebral salt wasting syndrome, Tuberculous meningitis, Hyponatremia

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