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Tuberculosis & Respiratory Diseases

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Vol.60 No.3
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다제내성 결핵에 의한 횡단척수염 1예

A case of Transverse Myelitis due to Multidrug-Resistant Tuberculosis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2006, v.60 no.3, pp.353-356
이광하 (울산의대)
심태선 (울산대학교)
나승원 (울산대학교)
박이내 (울산의대)
최혜숙 (울산의대)
정훈 (인제대학교)
전규략 (울산의대)
이광하, 심태선, 나승원, 박이내, 최혜숙, 정훈, & 전규략. (2006). 다제내성 결핵에 의한 횡단척수염 1예. Tuberculosis & Respiratory Diseases, 60(3), 353-356.
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Abstract

Acute transverse myelitis (TM) is a neurological syndrome caused by inflammation of the spinal cord. TM is rare but is frequently caused by viral or bacterial infections. TM caused by tuberculosis (TB) is extremely rare and there are no reports of TM caused by multidrug-resistant TB (MDR-TB). We report a case of acute TM due to MDR-TB in a 40-year-old man. The patient had been diagnosed with pulmonary TB and was started on the first-line anti-TB treatment. However, the chest radiographic findings were aggravated and neurological symptoms such as weakness in both lower extremities, sensory changes, and voiding difficulty were newly developed. The T2-weighted magnetic resonance image of the spine showed diffusely increased signal intensity in the spinal cord, particularly at the lower cervical and upper thoracic levels, without any definite evidence of myeloradicular compression, which is consistent with a diagnosis of TM. A drug susceptibility test revealed MDR and second-line anti-TB drugs were prescribed. The chest radiographic findings showed improvement after treatment, the mycobacterial culture converted to negative, the MRI findings improved, and there was partial improvement in the low extremity weakness. The patient has been prescribing second-line anti-TB medications for 14 months.(Tuberc Respir Dis 2006; 60: 353-356)

keywords
Transverse myelitis, Tuberculosis, Multidrug resistance, Mycobacterium tuberculosis, Transverse myelitis, Tuberculosis, Multidrug resistance, Mycobacterium tuberculosis

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Tuberculosis & Respiratory Diseases

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