고립성 폐결절로 발현한 파종성 림프절 외 변연부 B-세포 림프종 1예
A Case Report of Disseminated Extranodal Marginal Zone B-Cell Lymphoma of MALT Manifested by Solitary Pulmonary Nodule
김성률 (울산대학교)
제갈양진 (울산대학교)
차희정 (울산대학교)
김혁 (울산대학교)
정종필 (울산대학교)
박창률 (울산대학교)
박진우 (울산대학교)
우순주
임은아
이기영
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초록
MALT림프종은 질병의 진행이 느리고, 진단 당시 국소적인 병변이 대부분이며, 폐와 위장관을 동시에 침범하는 경우는 매우 드물다. 저자들은 흉부 단순촬영에서 고립성 폐결절이 발견된 73세 남자 환자에서 위, 폐, 골수를 침범한 파종성 MALT림프종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
- keywords
- Extranodal marginal zone B-cell lymphoma of MALT, Disseminated, Solitary pulmonary nodule., Extranodal marginal zone B-cell lymphoma of MALT, Disseminated, Solitary pulmonary nodule.
Abstract
Extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is usually indolent. Although it was reported recently that about 20-30% cases of MALT lymphoma presented with a disseminated disease at diagnosis, it was described as a disease localized at diagnosis and remaining stable for a prolonged period. However, only a few cases of MALT lymphoma involved the lung and gastrointestinal tract all at once. We report a case of a 73-year-old man with disseminated MALT lymphoma. He presented with non-productive cough, initial chest radiograph showed a nodule in the right lower lobe. The diagnosis of stage IV MALT lymphoma was made by CT scan, video-assisted thoracoscopic excisional biopy, gastrofiberscopic biopsy and bone marrow biopsy. The lymphoma involved the lung, stomach and bone marrow at the time of diagnosis. Because he refused chemotherapy, he discharged after Helicobacter pylori eradication without chemotherapy. Regular follow-up examination did not show any evidence of disease progression over 22 months. (Tuberc Respir Dis 2006; 61: 171-177)
- keywords
- Extranodal marginal zone B-cell lymphoma of MALT, Disseminated, Solitary pulmonary nodule., Extranodal marginal zone B-cell lymphoma of MALT, Disseminated, Solitary pulmonary nodule.
참고문헌
Zucca E, (1997) Primary extranodal non-Hodgkin’s lymphomas: part 1. gastrointestinal, cutaneous and genitourinary lymphomas,
Isaacson P, (1984) Extranodal malignant lymphoma arising from mucosa-associated lymphoid tissue,
Raderer M, (2000) Importance of extensive staging in patients with mucosa-associated lymphoid tissue(MALT)-type lymphoma,
Thieblemont C, (2000) Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed,
Graziadei G, (1998) Low-grade MALT lymphoma involving multiple mucosal sites and bone marrow,
Moon CM, (2003) A case of mucosa-associated lymphoid tissue lymphoma in the esophagus accompanied by bronchus-associated lymphoid tissue lymphoma,
Bae JY, (2005) A case of primary mucosa-associated lymphoid tissue lymphoma of the trachea and colon,
Isaacson P, (1983) Malignant lymphoma of mucosa-associated lymphoid tissue:a distinctive type of B-cell lymphoma,
Harris NL, (1994) A revised European-American classification of lymphoid neoplasms:a proposal from the International Lymphoma Study Group,
Kim JH, (2001) Clinical investigation of gastric MALT lymphoma,
Oh SY, (2000) Extra-gastric MALT lymphoma:analysis of 50 cases,
Jee SR, (2005) Low-grade mucosa-associated lymphoid tissue lymphoma of stomach,
Tsang RW, (2001) Stage I and II MALT lymphoma:results of treatment with radiotherapy,
Hitchcock S, (2002) Treatment outcome of mucosa-associated lymphoid tissue/marginal zone non-Hodgikin’s lymphoma,
Zinzani PL,, (2004) Fludarabine-containing chemotherapy as frontline treatment of nongastrointestinal mucosa-associated lymphoid tissue lymphoma,
Horning SJ, (1984) The natural history of initially untreated low-grade non-Hodgkin’s lymphomas,
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