바로가기메뉴

본문 바로가기 주메뉴 바로가기

원발성 폐 융모막암종 1예

A Case of Primary Choriocarcinoma of the Lung

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2006, v.61 no.6, pp.578-584
조영재 (서울의대)
유철규 (서울대학교)
심영수 (서울대학교)
김영환 (서울대학교)
한성구 (서울대학교)
임재준 (서울대학교)
이세원 (서울의대)
이상민 (서울대학교)
  • 다운로드 수
  • 조회수

초록

저자들은 뚜렷한 종양성 병변이 방사선학적으로는 물론 전신 PET에서도 유일하게 폐에서만 발견이 되었고, 산부인과적 검진 및 골반 MRI 검사에서도 원발성 종양을 의심할만한 병변이 발견되지 않았으며, 병리학적으로 면역조직화학염색을 통해 β-HCG에 양성인 원발성 폐 융모막암종의 증례를 경험하였기에 이 환자의 임상적 소견과 경과를 문헌 고찰과 함께 보고하는 바이다.

keywords
Primary choriocarcinoma, Lung, β-human chorionic gonadotropin (HCG), Primary choriocarcinoma, Lung, β-human chorionic gonadotropin (HCG)

Abstract

A primary choriocarcinoma of the lung is extremely rare, and difficult to distinguish from a metastatic choriocarcinoma considering that the lung is also one of the most frequent sites of metastasis. We report a 28-year-old woman patient who was initially misdiagnosed with an ectopic pregnancy and was operated on under the impression of an unidentified malignancy of the lung, which was finally proven to be a choriocarcinoma of the lung. A pelvic examination by a gynecologist, pelvic magnetic resonance imaging and whole body fluorodeoxyglucose positron emission tomography-computed tomography was performed in order to rule out a metastatic choriocarcinoma of the lung. After a curative operation, her serum β-human chorionic gonadotropin (HCG) level, which was highly elevated in the initial evaluation, had decreased dramatically to the normal range. She is currently being followed up regularly without any evidence of recurrence or elevation of her β-HCG level. (Tuberc Respir Dis 2006; 61: 578-584)

keywords
Primary choriocarcinoma, Lung, β-human chorionic gonadotropin (HCG), Primary choriocarcinoma, Lung, β-human chorionic gonadotropin (HCG)

참고문헌

1.

(2004) Primary choriocarcinoma of the lung,

2.

(2006) Primary pulmonary choriocarcinoma combined with adenocarcinoma,

3.

(1987) Primary choriocarcinoma of the lung,

4.

(1985) Primary choriocarcinoma of the lung,

5.

(2000) Primary choriocarcinoma and human chorionic gonadotrophin-producing giant cell carcinoma of the lung: are they independent entities?,

6.

(2004) Expanding the clinical development of bevacizumab,

7.

(1995) A rare case of primary pulmonary choriocarcinoma in a male immunohistochemical detection for human chorionic gonadotropin, epidermal growth factor (EGF) and EGF-receptor,

8.

(2006) Primary choriocarcinoma of the lung manifesting as diffuse alveolar hemorrhage,

9.

(1966) Gonadotropin-producing anaplastic large-cell carcinomas of the lung,

10.

(2002) A paraneoplastic syndrome mimicking extrauterine pregnancy,

11.

(2002) Use of urine pregnancy test for rapid diagnosis of primary pulmonary choriocarcinoma in a man,

12.

(1996) Extragonadal nongestational choriocarcinoma involving the lung:a report of three cases,

13.

(1989) Primary choriocarcinoma of the lung:report of a case treated with intensive multimodality therapy and review of the literature,

14.

(2005) Occult choriocarcinoma discovered by positron emission tomography/computed tomography imaging following a successful pregnancy,

15.

(1994) Primary lung choriocarcinoma masquerading as a metastatic gestational neoplasm,

16.

(1994) Primary lung choriocarcinoma masquerading as a metastatic gestational neoplasm,

Tuberculosis & Respiratory Diseases