소세포폐암에서 항암화학요법 중 발생한 치명적 종양용해증후군 1예
Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer
김민수 (원자력의학원)
안세한 (원자력의학원)
전세용 (원자력의학원)
윤정호 (원자력의학원)
한민성 (원자력의학원)
김철현 (원자력의학원)
이재철 (원자력의학원)
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초록
고형암에서의 종양용해증후군은 드물지만 발생하면 높은 사망률을 보이는 치명적인 합병증으로 외국에서는 지금까지 약 50여명의 증례가 보고되어 왔다. 우리 나라에서도 종 발생한다고 알려져 있지만 실제로 뒷받침 할만한 증례를 찾아 보기가 힘든 실정이었다. 이에 저자들은 소세포폐암에서 항암화학요법 도중 발생한 치명적 종양용해증후군 1예를 경험하였기에 문헌 고찰과 함께 이를 보고하는 바이다.
- keywords
- Small cell lung cancer, Tumor lysis syndrome
Abstract
Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor.
- keywords
- Small cell lung cancer, Tumor lysis syndrome
참고문헌
1. Hande KR, Garrow GC. Acute tumor lysis syndrome in patients with high- grade non-Hodgkin's lymphoma.Am J Med 1993;94:133-9.
2. Arrambide K, Toto RD. Tumor lysis syndrome. Semin Nephrol 1993;13:273-80.
3. Gemici C. Tumour lysis syndrome in solid tumours.Clin Oncol (R Coll Radiol) 2006;18:773-80.
4. Baeksgaard L, Sorensen JB. Acute tumor lysis syndrome in solid tumors-a case report and review of the literature. Cancer Chemother Pharmacol 2003;51:187-92.
5. Kallab AM, Jillella AP. Tumor lysis syndrome in small cell lung cancer. Med Oncol 2001;18:149-51.
6. Hussein AM, Feun LG. Tumor lysis syndrome after induction chemotherapy in small-cell lung carcinoma.Am J Clin Oncol 1990;13:10-3.
7. Beriwal S, Singh S, Garcia-Young JA. Tumor lysis syndrome in extensive-stage small-cell lung cancer. Am J Clin Oncol 2002;25:474-5.
8. Davidson MB, Thakkar S, Hix JK, Bhandarkar ND,Wong A, Schreiber MJ. Pathophysiology, clinical consequences,and treatment of tumor lysis syndrome. Am J Med 2004;116:546-54.
9. Kalemkerian GP, Darwish B, Varterasian ML. Tumor lysis syndrome in small cell carcinoma and other solid tumors. Am J Med 1997;103:363-7.
10. Cairo MS, Bishop M. Tumor lysis syndrome: new therapeutic strategies and classification. Br J Haematol 2004;127:3-11.
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