A Case of Posttraumatic Pleural Effusion with Perpheral Eosinophilia

Eosinophilic pleural effusions (EPE) are defined as those effusions that contain at least 10% eosinophils, and EPE can be associated with peripheral blood eosinophilia in a variety of systemic diseases. There have been a few cases that have addressed the association of peripheral blood eosinophilia and posttraumatic EPE, and this condition can be misdiagnosed as being the result of other causes due to the delayed presentation. We report here on a case of 47-year-old male who presented with eosinophilic pleural effusion associated with peripheral blood eosinophilia at 2 months after minor chest trauma. We excluded the other possible causes such as consumption of drugs, parasite infection, malignancy, diseases of pulmonary eosinophilic infiltration, autoimmune diseases and pulmonary thromboembolism. We observed his clinical course without specific treatment. Three months later, the pleural effusion completely disappeared and the number of peripheral eosinophils returned to normal.

keywords: Pleural effusion, Eosinophilia, Trauma

Reference

1. Kalomenidis I, Light RW. Pathogenesis of the eosinophilic pleural effusions. Curr Opin Pulm Med 2004;10:289-93.

2. Martinez-Garcia MA, Cases-Viedma E, Cordero-Rodriguez PJ, Hidalgo-Ramirez M, Perpina-Tordera M,Sanchis-Moret F, et al. Diagnostic utility of eosinophilic in the pleural effusion. Eur Respir J 2000;15:166-9.

3. Rubins JB, Rubins HB. Etiology and prognostic significance of eosinophilic pleural effusions. A prospective study. Chest 1996;110:1271-4.

4. Maltais F, Laberge F, Cormier Y. Blood hypereosinophilia in the course of posttraumatic pleural effusion.Chest 1990;98:348-51.

5. de Blay F, Aykut-Baturalp A, Goetz J, Purohit A, Perez-Infante A, Hauptmann G, et al. Post-traumatic pleural effusion: demonstration of local complement comsumption.Respir Med 1997;91:373-5.

6. Inoue S, Tanaka H, Fujita E, Kubo M, Hirakata H,Fukushima Y, et al. Eosinophilic pleural effusion and peripheral eosinophilia--an umcommon complication of thoracoscopic parathyroidectomy. Nephrol Dial Transplant 1998;13:2929-31.

7. Schandene L, Namias B, Crusiaux A, Lybin M, Devos R, Velu T, et al. IL-5 in post-traumatic eosinophilic pleural effusion. Clin Exp Immunol 1993;93:115-9.

8. Mohamed KH, Abdelhamid AI, Lee YC, Lane KB,Conner B, Hawthorne M, et al. Pleural fluid level of interleukin-5 and eosinophils are closely correlated.Chest 2002;122:576-80.

9. Kalomenidis I, Stathopoulos GT, Barnette R, Guo Y,Peebles RS, Blackwell TS, et al. Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions. Chest 2005;127:2094-100.

10.

10. Kalomenidis I, Guo Y, Peebles RS, Lane KB, Papiris S,Elias J, et al. Pneumothorax-associated pleural eosinophilia in mice is interleukin-5 but not interleukin-13 dependent. Chest 2005;128:2978-83.

11.

11. Perens GS, Shannon KM, Levi DS, Drant S. Successful treatment of eosinophilic pleural effusions following congenital heart surgery. Pediatr Cardiol 2006;27:168-9.

12.

12. Ishiura Y, Fujimura M, Nakamura N, Jokaji H, Minami S, Matsuda T. Intrapleural corticosteroid injection therapy for post-traumatic eosinophilic pleural effusion.Respir Med 1996;90:501-3.

13.

13. Blackwell GJ, Carnuccio R, Di Rosa M, Flower RJ,Langham CS, Parente L, et al. Glucocorticoids induce the formation and release of anti-inflammatory and anti- phospholipase proteins into the peritoneal cavity in the rat. Br J Pharmacol 1982;76:185-94.

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Article Contents

Vol.64 No.5

A Case of Posttraumatic Pleural Effusion with Perpheral Eosinophilia

Abstract

Reference

Tuberculosis & Respiratory Diseases