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Tuberculosis & Respiratory Diseases

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Vol.64 No.5
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A Case of Bronchiectasis with High Serum CA19-9

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.64 no.5, pp.383-386












& (2008). A Case of Bronchiectasis with High Serum CA19-9. Tuberculosis & Respiratory Diseases, 64(5), 383-386.
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Abstract

An elevated serum CA19-9 level is an indication of pancreatic and biliary tract cancer. However, it has recently become known that nonmalignant gastrointestinal diseases and a variety of nonmalignant respiratory diseases, such as idiopathic interstial pneumonia, collagen vascular disease associated lung diseases, diffuse panbronchiolitis and bronchiectasis, can also show an elevated serum CA19-9 level. We recently encountered a case of bronchiectasis with persistently elevated serum CA19-9, but without any evidence of malignant disease in endoscopic retrograde pancreatocholangiography, abdominal computed tomography, and positron emission tomography. After serial follow-up of 3 years and 10 months, there was still no evidence of cancer. It is believed that the elevated serum CA19-9 level was due to bronchiectasis. An elevated serum CA19-9 level should be interpreted carefully with the patients' clinical condition.

keywords
CA19-9, Bronchiectasis, Benign

Reference

1.

1. Plebani M, Basso D, Panozzo MP, Fogar P, Del Favero G, Naccarato R. Tumor markers in the diagnosis, monitoring and therapy of pancreatic cancer: state of the art. Int J Biol Markers 1995;10:189-99.

2.

2. Levy C, Lymp J, Angulo P, Gores GJ, Larusso N, Lindor K. The value of serum CA19-9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis. Dig Dis Sci 2005;50:1734-40.

3.

3. Shimizu Y, Hamada T, Tanaka Y, Sasaki A, Nemoto T.Colonization of CA19-9 and KL-6 to epithelial cells in dilated bronchioles in a patient with idiopathic pulmonary fibrosis complicated by diffuse alveolar damage.Respirology 2002;7:281-4.

4.

4. Mukae H, Hirota M, Kohno S, Komori K, Fukushima K, Hiratani K, et al. Elevation of tumor-associated carbohydrate antigens in patients with diffuse panbronchiolitis.Am Rev Respir Dis 1993;148:744-51.

5.

5. Ishiura Y, Fujimura M, Minami S, Ueda A, Iwata M,Watanabe K, et al. Increased CA19-9 level in serum and bronchoalveolar lavage fluid from a patient with pulmonary tuberculosis. Nihon Kyobu Shikkan Gakkai Zasshi 1996;34:477-81.

6.

6. Shimizu Y, Hamada T, Tanaka Y, Sasaki A, Nemoto T.Colocalization of CA19-9 and KL-6 to epithelial cells in dilated bronchioles in a patient with idiopathic pulmo nary fibrosis complicated by diffuse laveolar damage.Respirology 2002;7:281-4.

7.

7. Kodama T, Satoh H, Ishikawa H, Ohtsuka M. Serum levels of CA19-9 in patients with nonmalignant respiratory diseases. J Clin Lab Anal 2007;21:103-6.

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