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Vol.65 No.1
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A Case of Intermediate Grade Bronchial Mucoepidermoid Carcinoma and Review in Korean Cases

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.65 no.1, pp.41-48










& (2008). A Case of Intermediate Grade Bronchial Mucoepidermoid Carcinoma and Review in Korean Cases. Tuberculosis & Respiratory Diseases, 65(1), 41-48.
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Abstract

Bronchial mucoepidermoid carcinoma is uncommon, representing 0.2% of all lung tumors. The disease usually presents with symptoms of airway obstruction and recurrent pneumonia. It is commonly classified into two grades in Korea, low and high. We report a case of a bronchial mucoepidermoid carcinoma in a 40-year-old woman who complained of symptoms of an upper respiratory infection. The histological grade after a bronchoscopic biopsy was intermediate. A left upper lobectomy was performed as treatment. The TNM stage of this case was IA (T1N0M0). In addition, 25 cases of bronchial mucoepidermoid carcinoma from 1984 in Korea are also reviewed from the viewpoint of the relationship between the histological grade, TNM stage and clinical course of the tumor.

keywords
Bronchial mucoepidermoid carcinoma, Intermediate grade, TNM stage, PET

Reference

1.

1.Colby T, Koss M, Travis W. Tumors of the lower respiratory tract. 3rd series. Washington, DC: Armed Forces Institute of Pathology; 1995.

2.

2.Heitmiller RF, Mathisen DJ, Ferry JA, Mark EJ, Grillo HC. Mucoepidermoid lung tumors. Ann Thorac Surg 1989;47:394-9.

3.

3.Conlan AA, Payne WS, Woolner LB, Sanderson DR. Adenoid cystic carcinoma (cylindroma) and mucoepidermoid carcinoma of the bronchus. Factors affecting survival. J Thorac Cardiovasc Surg 1978;76:369-77.

4.

4.Smetana HF, Iverson L, Swan LL. Bronchogenic carcinoma: an analysis of 100 autopsy cases. Mil Surg 1952;111:335-51.

5.

5.Liu X, Adams AL. Mucoepidermoid carcinoma of the bronchus. Arch Pathol Lab Med 2007;131:1400-4.

6.

6.Pandya H, Matthews S. Case report: Mucoepidermoid carcinoma in a patient with congenital agenesis of the left upper lobe. Br J Radiol 2003;76:339-42.

7.

7.Tonon G, Gehlhaus KS, Yonescu R, Kaye FJ, Kirsch IR. Multiple reciprocal translocations in salivary gland mucoepidermoid carcinomas. Cancer Genet Cytogenet 2004;152:15-22.

8.

8.Barrett W, Heaps LS, Diaz S, Sharma P, Arbuckle S, Smith A. Mucoepidermoid carcinoma of the bronchus in a 15-year-old girl with complex cytogenetic rearrangement involving 11q and over-expression of cyclin D1. Med Pediatr Oncol 2002;39:49-51.

9.

9.Niggemann B, Gerstner B, Guschmann M, Paul K, Wit J, Mau H, et al. An 11-yr-old male with pneumonia and persistent airway obstruction. Eur Respir J 2002;19: 582-4.

10.

10.Ishizumi T, Tateishi U, Watanabe S, Maeda T, Arai Y. F-18 FDG PET/CT imaging of low-grade mucoepidermoid carcinoma of the bronchus. Ann Nucl Med 2007;21:299-302.

11.

11.Kinoshita H, Shimotake T, Furukawa T, Deguchi E, Iwai N. Mucoepidermal carcinoma of the lung detected by positron emission tomography in a 5-year-old girl. J Pediatr Surg 2005;40:E1-3.

12.

12.Chin CH, Huang CC, Lin MC, Chao TY, Liu SF. Prognostic factors of tracheobronchial mucoepidermoid carcinoma: 15 years experience. Respirology 2008; 13:275-80.

13.

13.Matsuzaki Y, Shibata K, Yoshioka M, Inoue M, Sekiya R, Onitsuka T, et al. Successful treatment of bronchial mucoepidermoid carcinoma in an 11-year-old boy by bronchoplasty: report of a case. Surg Today 1996;26: 64-7.

14.

14.Klacsmann PG, Olson JL, Eggleston JC. Mucoepidermoid carcinoma of the bronchus: an electron microscopic study of the low grade and the high grade variants. Cancer 1979;43:1720-33.

15.

15.Carter D, Eggleston JC. Tumors of the lower respiratory tract. Atlas of tumour pathology. Washington, DC: Armed Forces institute of Pathology; 1980.

16.

16.Brandwein MS, Ivanov K, Wallace DI, Hille JJ, Wang B, Fahmy A, et al. Mucoepidermoid carcinoma: a clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol 2001;25:835-45.

17.

17.Hicks MJ, el-Naggar AK, Flaitz CM, Luna MA, Batsakis JG. Histocytologic grading of mucoepidermoid carcinoma of major salivary glands in prognosis and survival: a clinicopathologic and flow cytometric investigation. Head Neck 1995;17:89-95.

18.

18.Shilo K, Foss RD, Franks TJ, DePeralta-Venturina M, Travis WD. Pulmonary mucoepidermoid carcinoma with prominent tumor-associated lymphoid proliferation. Am J Surg Pathol 2005;29:407-11.

19.

19.Han SW, Kim HP, Jeon YK, Oh DY, Lee SH, Kim DW, et al. Mucoepidermoid carcinoma of lung: potential target of EGFR-directed treatment. Lung Cancer 2008; 61:30-4.

20.

20.Molina JR, Aubry MC, Lewis JE, Wampfler JA, Williams BA, Midthun DE, et al. Primary salivary gland-type lung cancer: spectrum of clinical presentation, histopathologic and prognostic factors. Cancer 2007;110: 2253-9.

21.

21.Song IS, Cho KH, Lee HG. Mucoepidemoid tumor of the bronchus. Korean J Thorac Cardiovasc Surg 1984; 17:740-6.

22.

22.Ann B, Cha HD, Kwon YM, Kang JM. Childhood bronchial mucoepidermoid tumor: a case report and review of the literature. Korean J Pediatr 1985;28:102-6.

23.

23.Byun HS, Oh BS, Lee DJ. Bronchial mucoepidermoid carcinoma: 1 case report. Korean J Thorac Cardiovasc Surg 1988;21:941-7.

24.

24.Kim JH, Kim YB, Kim CS, Kim DS, Kim RH, Kim CH, et al. A report of two cases of mucoepidermoid carcinoma. Tuberc Respir Dis 1993;40:58-66.

25.

25.Jeong JM, Song JY, Hong JR, Kim YJ, Kim MS. A case of mucoepidermoid carcinoma in pulmonary tuberculosis patient. Tuberc Respir Dis 1994;41:429-34.

26.

26.Yim JY, Son HY, Park KR, Lee KH, Shin MS, Chang JH, et al. A case of bronchial mucoepidermoid carcinoma. Tuberc Respir Dis 1997;44:1132-9.27.Kim CM, Sohn JW, Yang SC, Yoon HJ, Shin DH, Park SS, et al. A case of bronchial mucoepidermoid carcinoma associated with adenocarcinoma. Tuberc Respir Dis 1997;44:677-83.

27.

28.Kim YJ, Park JY, Shin MC, Bae MS, Kim JS, Chae SC, et al. A clinical review of mucoepidermoid carcinoma of the lung in Korea. Tuberc Respir Dis 1992;45: 311-21.

28.

29.Choi YH, Kim TS, Shin JS, Hwang JJ, Sohn YS, Kim HJ, et al. Low grade mucoepidermoid carcinomas of the lung. Korean J Bronchoesophagol 1998;4:225-30.

29.

30.Son JA, Koo HH, Lee SI, Kim JG. Mucoepidermoid carcinoma of the bronchus in a 9-year-old-child. J Korean Pediatr Soc 1998;41:837-40.

30.

31.Lee SY, Lim MR, Koo SE, Kim Jh, Hong SJ. A case of mucoepidermoid carcinoma of bronchus. Pediatr Allergy Respir Dis 2002;12:160-5.

31.

32.Yun SW, Kim DK, Park CR, Park SI. Mucoepidermoid carcinoma of the bronchus in a 10-year-old child. Korean J Thorac Cardiovasc Surg 2002;35:760-3.

32.

33.Yoon KC, Park YT. Mucoepidermoid carcinoma of the lung. Korean J Thorac Cardiovasc Surg 2004;37:92-4.

33.

34.Ryoo JY, Kim YS, Kim WS, Chang WI, Joo M. Mucoepidermoid carcinoma of the right lower lobe bronchus: a case report. Korean J Thorac Cardiovasc Surg 2004; 37:955-8.

34.

35.Lee SJ, Cho SM, Koo KM. A case of bronchial mucopeidermoid carcinoma in a 11-year-old Child. Dongguk J Med 2004;11:389-94.

35.

36.Park YH, Kang JW, Kim KW, Kim ES, Jee HM, Sohn MH, et al. Mucoepidermoid carcinoma in a 12-year-old boy. Pediatr Allergy Respir Dis 2007;17:420-4.

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