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Tuberculosis & Respiratory Diseases

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Vol.65 No.1
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A Case of Acute Myeloid Leukemia with Multilineage Dysplasia accompanying Malignant Pleural Effusion

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.65 no.1, pp.49-51








& (2008). A Case of Acute Myeloid Leukemia with Multilineage Dysplasia accompanying Malignant Pleural Effusion. Tuberculosis & Respiratory Diseases, 65(1), 49-51.
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Abstract

We report a case of acute myeloid leukemia with multilineage dysplasia accompanying malignant pleural effusion. A 73 year-old male patient was admitted complaining of febrile sensations and right chest pain. The cytology of the pleural fluid revealed malignant pleural effusion showing many blasts, which had previously been identified in his bone marrow when he was diagnosed with acute myeloid leukemia with multilineage dysplasia two months earlier. His age and poor general condition had precluded chemotherapy with the exception of hydroxyurea and conservative treatment. Unfortunately, he succumbed to the disease 4.5 months after diagnosis. This case highlights the importance of determining if the pleural effusion of acute leukemia is malignant or not because it can suggest a pleural metastasis and influence the prognosis.

keywords
Malignant pleural effusion, Acute myeloid leukemia with multilineage dysplasia, Extramedullary involvement

Reference

1.

1.Haas AR, Sterman DH, Musani AI. Malignant pleural effusions: management options with consideration of coding, billing, and a decision approach. Chest 2007; 132:1036-41.

2.

2.Fatih T, Selim Y, Mesut A, Demirel YN, Yuksel P. An unusual cause of unilateral pleural effusion in the setting of aortic stenosis: acute myeloid leukemia. Intern Med 2007;46:325-7.

3.

3.Yim JJ, Lee JH, Yoo CG, Chung HS, Han SK, Shim YS, et al. The incidences and characteristics of malignant pleural effusions according to histologic types. Tuberc Respir Dis 1998;45:565-73.

4.

4.Alexandrakis MG, Passam FH, Kyriakou DS, Bouros D. Pleural effusions in hematologic malignancies. Chest 2004;125:1546-55.

5.

5.Disel U, Yavuz S, Paydas S, Sahin B, Zeren H. Extramedullary relapse in the pleura in acute promyelocytic leukemia. Leuk Lymphoma 2003;44:189-91.

6.

6.Dix DB, Anderson RA, McFadden DE, Wadsworth LD. Pleural relapse during hematopoietic remission in childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol 1997;19:470-2.

7.

7.Ruckdeschel JC. Management of malignant pleural effusions. Semin Oncol 1995;22:58-63.

8.

8.Light RW, Hamm H. Malignant pleural effusion: would the real cause please stand up? Eur Respir J 1997; 10:1701-2.

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